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SynKinase
ZSTK474
71
CHF
CHF 71.00
In stock
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Product Details | |
---|---|
Synonyms | ZSTK-474 |
Product Type | Chemical |
Properties | |
Formula | C19H21F2N7O2 |
MW | 417.4 |
CAS | 475110-96-4 |
Purity Chemicals | ≥95% |
Appearance | Solid. |
Solubility | Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. |
Declaration | Manufactured by SynKinase. |
Other Product Data |
Target: PI3K | Kinase Group: Lipid Kinase | Substrate: Lipid Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
InChi Key | HGVNLRPZOWWDKD-UHFFFAOYSA-N |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
Description
ZSTK474 Inhibits all four PI3K isoforms in an ATP-competitive manner. IC(50) is approximately 37nM.
Product References
- Antitumor activity of ZSTK474, a new phosphatidylinositol 3-kinase inhibitor: S. Yaguchi, et al.; J. Natl. Cancer Inst. 98, 545 (2006)