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SynKinase
BGT226 maleate
CHF 0.00
In stock
SYN-1178-M0011 mgCHF 128.00
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SYN-1178-M100100 mgINQ
| Product Details | |
|---|---|
| Synonyms | NVP-BEZ226; BEZ-226 |
| Product Type | Chemical |
| Properties | |
| Formula | C28H25F3N6O2 . C4H4O4 |
| MW | 534.5 . 116.1 |
| CAS | 1245537-68-1 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: PI3K | Kinase Group: Lipid Kinase | Substrate: Lipid Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | YUXMAKUNSXIEKN-BTJKTKAUSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
NVP-BGT226 is a novel, orally bioavailable small-molecule inhibitor of phosphoinositol-3-kinase and mammalian target of rapamycin with an IC(50) of 1nM.
Product References
- Simultaneous targeting of PI3K and mTOR with NVP-BGT226 is highly effective in multiple myeloma: P. Baumann, et al.; Anticancer Drugs 23, 131 (2012)
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