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Product Flyers & Technical Notes
| Alithea Genomics MERCURIUS Product Flyer - RNA Sequencing Kits Alithea Genomics first products include the MERCURIUS BRB-Seq™ kits, which enable cost-effective, high-throughput RNA-seq library preparation from a broad range of RNA samples. Alithea's products are ideal for large-scale RNA sequencing (transcriptomic) studies such as biomarker discovery, antibody development and drug screening. For an overview on AdipoGen Life Sciences entire panel of "MERCURIUS Products" please search this website. Released - March 2022 |
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| The Ubiquitin-Proteasome System (UPS) The ubiquitin-proteasome system (UPS) and the autophagic-lysosomal pathway are the two major degradation systems for both native and misfolded proteins in eukaryotic cells. Proteasome inhibition has therefore implications in a number of human diseases such as cancer, inflammation and ischemic stroke and is an important therapeutic target. Adipogen Life Sciences offers a broad panel of proteasome inhibitors, modulators and fluorogenic substrates, and a panel of proteasome complex proteins and kits. For an overview on AdipoGen Life Sciences entire panel of "Proteasome-related Products" please search this website. Released - November 2021 |
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RevMAb Biosciences - Mutant-specific Rabbit Monoclonal Antibodies For more information visit our RevMAb Biosciences landing page. Released - April 2021 |
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RevMAb Biosciences - Histone H3 Mutation Antibodies For more information visit our RevMAb Biosciences landing page. Released - April 2021 |
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Reagents for SARS-CoV-2/COVID-19 Research - Overview Flyer For more information visit AdipoGen Life Sciences landing page on COVID-19. Released - July 2020 |
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AdipoGen Insights: Interleukin-33 IL-33 is a nuclearassociated cytokine that is normally released by damaged or necrotic cells acting as an “alarmin”, an immediate indicator of tissue stress. IL-33 is a potent inducer of type 2 immune responses in the contexts of parasite infections and allergic asthma. New studies have also extended the biology of IL-33 with other functions: i) inducing brown and beige adipocyte thermogenesis and to promote insulin secretion by pancreatic islets; ii) facilitating Treg proliferation to suppress autoimmunity and to potentiate neurological recovery; and iii) exerting multiple roles in the brain. For more information visit AdipoGen Life Sciences landing page on Interleukin-33 (in process). Released - January 2020 Version with Weblinks - Released November 2020 |
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AdipoGen Insights: The Tubulin Code: Posttranslational Modifications of Tubulin For more information visit AdipoGen Life Sciences landing page on The Tubulin Code. Released - January 2020 Version with Weblinks - Released November 2020 |
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AdipoGen Insights: Progranulin - Marker of Neuroinflammation TAG-FREE - Progranulin Recombinant Proteins For more information visit AdipoGen Life Sciences landing page on Progranulin. Released - November 2019 Version with Weblinks - Released November 2020 |
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Glycobiology Research Version with Weblinks - Released November 2020 |
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| Erythroferrone (human) ELISA Kit - The only Specific & Sensitive Assay on the Market! • High Specificity For an overview on AdipoGen Life Sciences panel of Iron Metabolism-Related Products please search this website. Version with Weblinks - Released November 2020 |
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Advanced Immune Regulation Reagents - 3rd Edition Version with Weblinks - Released November 2020 |
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AdipoGen Insights - Autoimmune Disease Biomarkers APRIL & BAFF For more information visit AdipoGen Life Sciences landing page Autoimmune Diseases Biomarkers. Released - February 2019 Version with Weblinks - Released November 2020 Latest Update - October 2021 |
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AdipoGen Insights - Gasdermin D Signaling & Inflammasome Research Includes Unique Tool to Measure Pyroptosis! For more information visit AdipoGen Life Sciences landing page Gasdermin Signaling. |
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| A New Tool To Measure Pyroptosis - Poster at EMBO Inflammasome Symposia Pyroptosis is an inflammatory programmed cell death that is initiated in response to pathogen- or host-derived perturbations of the cytosol. Pyroptosis is induced by inflammatory caspases, such as caspase-1 and −11 in mice that are activated by a high molecular weight complex, called inflammasomes. Gasdermin D (GSDMD) is the central mediator of pyroptotic cell death downstream of both caspase-1 and caspase-11. GSDMD is cleaved by these caspases into a 31 kDa N-terminal fragment (GSDMDNterm) that forms pores into the plasma membrane and a 22 kDa C-terminal fragment (GSDMDCterm). This poster presents data obtained with a new Gasdermin D (mouse) ELISA kit based on antibodies developed against the C-terminal fragment of Gasdermin D (mouse). For an overview on AdipoGen Life Sciences entire panel of Gasdermin Research Products please search this website. Released - September 2018 |
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| Key Inflammasome Research Tools • Unique Antibodies: NLRP3 mAb; Asc pAb; Caspase-1 (p10) mAb; Caspase-1 (p20) mAb • Potent Activators: Monosodium urate (MSU), Nigericin • Potent Inhibitors: MCC-950; Isoliquiritigenin; 3-Hydroxybutyric acid; Arglabin and much more For an overview on AdipoGen Life Sciences entire panel of Inflammasome Research Products please search this website. Released - June 2018 |
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| Innaxon - Bringing Innate Immunity to Life Innaxon develops and manufactures defined “Immunoceuticals” of the highest activity and purity for pre-clinical research and development applications for vaccine adjuvants and immunotherapy. Their unique biological and synthetic Toll-like Receptor (TLR) ligands are well-characterized and effective biological response modifiers of inappropriate or disproportionate immune responses. Innaxon's product panel is exculsively available through AdipoGen Life Sciences. For an overview on Innaxon's entire panel of TLR Reseach Products please search this website. Released - June 2018 |
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| Interleukin-36γ - An Important Biomarker for Psoriasis AdipoGen Life Sciences offers a comprehensive panel of new and innovative products in the Skin Inflammation Research Field. This flyer introduces the new sensitive IL-36γ (human) ELISA Kit and gives an overview on unqiue proteins and Detection Systems in this research field, all developed by AdipoGen Life Sciences. For an overview on AdipoGen Life Sciences entire panel of Skin Inflammation Research please search this website. Released - September 2017 |
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| Advanced Immune-Regulation Reagents - 2nd Edition AdipoGen Life Sciences offers a comprehensive panel of new and innovative products in the Immune-Regulation Research Field. This flyer gives an overview on unqiue and the newest antibodies, proteins, ELISA kits and small molecules developed by AdipoGen Life Sciences. For an overview on AdipoGen Life Sciences entire panel of Immune-Regulation Products please search this website. Released - June 2017 |
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| DYRK Inhibitors AdipoGen Life Sciences offers a comprehensive panel of DYRK1A inhibitors and related Kinase Inhibitors, which are important targets for cancer and neurodegenerative diseases research. For an overview on AdipoGen Life Sciences entire panel of "DYRK1A inhibitors" please search this website. Released - May 2017 |
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| Unique Natural Products & Rare Antibiotics - In Collaboration with the Kitasato Institute AdipoGen Life Sciences offers a comprehensive panel of Unique Natural Products & Rare Antibiotics discovered by the Nobel Prize Awarded Kitasato Institute for Life Sciences. For an overview on AdipoGen Life Sciences entire panel of "Natural Products & Rare Antibiotics" please search this website. Released - December 2016 |
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| Commodity Small Molecules AdipoGen Life Sciences offers a comprehensive panel of Standard & Commodity Biochemicals. This flyer gives an overview on a panel of selected small molecules. For an overview on AdipoGen Life Sciences entire panel of Commodity Biochemicals please search this website. Released - September 2016 |
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| Multimeric Ligands™ - Manufactured by AdipoGen Life Sciences AdipoGen offers the broadest selection of TNF Ligands Multimeric Proteins, with higher or equal activity and lower endotoxin levels compared to the competition. AdipoGen® TNF Ligands Multimeric Proteins are high activity constructs in which two trimeric TNFSF ligands are linked via the oligomeric collagen domain of ACRP30 [ACRP30headless] and therefore mimic the membrane-bound forms of the proteins. See www.multimericligands.com for an overview on all MultimericLigands. Released - April 2016 |
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| CD1d Ligands - Potent iNKT Stimulators • α-Galactosylceramide and Derivatives • Mannosylceramides • Gangliosides and Derivatives For an overview on AdipoGen Life Sciences entire panel of "CD1d Ligands" please search this website. Released - February 2016 |
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| Unique Natural Products & Rare Antibiotics • Compounds from Plant Sources • Compounds from Marine Sources • Compounds from Bacterial Sources • Compounds from Fungal Sources For an overview on AdipoGen Life Sciences entire panel of "Natural Products & Rare Antibiotics" please search this website. Released - September 2015 |
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| Netrin-1 for Generation of iPS Cells - The 5th Key Reprogramming Factor Adipogen Life Sciences offers unique, stable & biological active recombinant human Netrin-1 proteins, that can be used for generation of iPS cells and pluripotency maintenance of embryonic stem cells, as described in D. Ozmadenci, et al. (2015). For more information on AdipoGen Life Sciences Netrin-1 Products please search this website. Released - August 2015 |
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| Angiogenesis Research Tools Potent Human & Mouse Ang-2 Blocking Antibodies Potent functionally Active Ang-1 & Ang-2 Proteins Human Tie-2 Specific Antibodies Biologically Active Notch Ligands and Specific Notch Receptor Antibodies VEGF: Proteins, Antibodies and Potent Small Molecule Inhibitor SAG − Shh Agonist & Potent Activator of VEGF Biologically Active Human Netrin-1Periostin [OSF2] − Tumor Angiogenesis Marker For an overview AdipoGen Life Sciences entire panel of Angiogenesis Research Products please search this website. Released - May 2015 |
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| Cancer Research AdipoGen Life Sciences offers a comprehensive panel of new and innovative products for the advancement of Cancer Research. This flyer gives an overview on unqiue antibodies, proteins, ELISA kits and small molecules. For an overview on AdipoGen Life Sciences entire panel of Cancer Research Products please search this website. Released - March 2015 |
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| Chemodex - Chemistry is our Passion - 2nd Edition Chemodex is a Swiss manufacturer of: • Common and New Fluorescent Probes • Stains/Labels/Dyes • Markers & Probes • Metabolites • Building Blocks & Small Molecules Released - November 2014 |
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| Myokines - Muscle, Exercise & Obesity Skeletal muscles secrete cytokines and growth factors, called myokines that can potentially act in an autocrine, a paracrine and/or an endocrine manner to modulate metabolic, inflammatory and other processes. AdipoGen Life Sciences offers a broad range of proteins and small molecules to study the interactions of muscles, exercise and obesity. Released - October 2014 |
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| Modulators of Autophagy Signaling AdipoGen offers a broad range of small molecules that can be used to modulate the autophagy process. This includes mTOR complex inhibitors and activators, preautophagosome (PAS) / initiation & nucleation modulators, autophagosome-lysosome fusion & degradation modulators and proteasome inhibitors. For an overview on AdipoGen Life Sciences entire panel of Autophagy-related Products please search this website. Released - May 2014 |
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| Chemodex - Chemistry is our Passion - 1st Edition Chemodex is a Swiss manufacturer of: • Common and New Fluorescent Probes • Stains/Labels/Dyes • Markers & Probes • Metabolites • Building Blocks & Small Molecules Released - February 2014 |
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| Ageladine A - Cell permeable, Non-toxic, pH-dependent Fluorescent Dye for Live Imaging Ageladine A is isolated from the marine sponge Agelas nakamurai. It exhibits in vitro and in vivo antiangiogenic activity with selective inhibition of kinases including dual specificity tyrosinephosphorylation-regulated kinase (DYRK)1A and DYRK2. Recently it was shown to be a unique cell permeable, non-toxic, pH-dependent fluorescent dye excellent for live imaging. Released - January 2014 |
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| JaICA - Unique Oxidative Stress Markers - Update 2014 The Japan Institute for the Control of Aging (JaICA) develops and manufactures research reagents to detect oxidative stress markers for DNA oxidation, Lipid oxidation, Protein oxidation and antioxidants. The monoclonal antibodies and ELISA kits detect products of oxidative damage caused by reactive oxygen species. The JaICA products are well known in the research community and cited in many scientific publications. For an overview on JaICA's "Oxidative Markers" please search this website. Released - February 2014 |
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| NAD+ Metabolome Supplement Flyer – From De Novo to Salvage Pathway Tryptophan (Trp) is an essential amino acid that cannot be synthesized by the organism and therefore must be part of our diet. It acts as building block in protein biosynthesis and is the only precursor for the endogenous de novo biosynthesis of nicotinamide adenine dinucleotide (NAD+). The first, rate-limiting step in the biosynthesis of NAD+ is the conversion of tryptophan to N-formylkynurenine, catalyzed by two enzymes, either indoleamine 2,3-dioxygenase (IDO) or tryptophan 2,3-dioxygenase (TDO), both requiring molecular oxygen. For an overview on AdipoGen Life Sciences entire panel of NAD Metabolome reagents please search this website. Released - July 2013 Only PDF version available |
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| NAD+ Metabolome – Linking Energy Metabolism and Cancer Many and various NAD+-dependent signaling pathways regulate fundamental processes such as transcription, DNA repair, cell cycle progression, apoptosis, proliferation, survival and metabolism, which are linked to cancer development. Targeting the NAD+ metabolism, its synthesis and signaling pathways (PARPs, SIRTs, MARTs, CD38) are promising concepts for cancer treatment. AdipoGen offers a broad panel of biologically active enzymes, antibodies, ELISA Kits and small molecules modulators for NAD+/Energy Metabolism research. For an overview on AdipoGen Life Sciences entire panel of NAD Metabolome reagents please search this website. Released - April 2013 |
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| Ancell Corporation - Monoclonal Antibodies Overview Ancell's extensive panel of human CD antibodies is produced by its experienced in-house development team. The products are purified and conjugated under optimized conditions and rigorously tested in cell lines and human samples. Most of the antibodies are variously labeled to perform in multiple applications, including flow cytometry, immunohistochemistry and immunofluorescence. Several antibodies have functional applications (which may be used for activation, neutralization or blocking studies). For an overview on the entire Ancell product portfolio please search this website. Released - April 2012 |
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| Cytoskeleton - Focus Microtubules Microtubules are the largest cytoskeletal components involved in intracellular transport (cell signaling), cell migration/trafficking, cell division and proliferation. Understanding of the cell structure and function is essential for gaining deeper knowledge of normal pathways such as morphogenesis, wound healing, neurogenesis and immune response, as well as abnormal processes such as metastasis and tumor-related angiogenesis. For an overview on AdipoGen Life Sciences entire panel of microtubule-related reagents please search this website. Released - March 2012 |
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| Kdo2-Lipid A - TLR4 Agonist Kdo2-Lipid A is a defined substructure of the Re mutant of lipopolysaccharide (LPS). It is a strong activator (<10ng/ml) of macrophages that signals via the toll-like receptor 4 (TLR4). Released - August 2010 Only PDF version available |
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