AdipoGen Life Sciences

anti-Tim-3 (mouse), mAb (TI 339H)

CHF 110.00

In stock

AG-20A-0029-C05050 µgCHF 110.00

AG-20A-0029-C100100 µgCHF 190.00

Figure 1: Western blot analysis using anti-TIM-3 (mouse), mAb (TI 339H) (Prod. No. AG-20A-0029) at 1:5'000 dilution.
1: Transfected mouse Tim-3 full length cell lysate (HEK 293).
2: Transfected vector only cell lysate.

Specifications / Handling

More Information
Product Details
Synonyms	TIM3; TIMD3; Hepatitis A Virus Cellular Receptor 2; HAVcr-2; T Cell Immunoglobulin and Mucin Domain-containing Protein 3
Product Type	Monoclonal Antibody
Properties
Clone	TI 339H
Isotype	Rat IgG2aκ
Immunogen/Antigen	Recombinant mouse Tim-3.
Application	ELISA: (direct or indirect: 1:2'000-1:10'000) Western blot: (1:500-1:1'000 using ECL. Suggested blocking and dilution buffer is TBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature). Optimal conditions should be determined individually for each application. Note: Tested on recombinant proteins and/or target-protein transfected cell lines in ELISA, Western Blot and/or FACS.
Crossreactivity	Mouse
Specificity	Recognizes mouse Tim-3.
Purity Detail	Protein G-affinity purified.
Concentration	1mg/ml
Formulation	Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Isotype Negative Control	Rat IgG2a Isotype Control
RRID	AB_2490111
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Use/Stability	Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

Tim-3 is a Th1-specific cell surface protein. It is expressed selectively by differentiated CD4+Th1 and CD8+Tc1 cells, but is absent on CD4+Th2 and CD8+ Tc2 cells. The Tim gene family has an important role in the regulation of autoimmunity and allergies.

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