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AdipoGen Life Sciences
anti-Ribosomal Protein S3 (human), mAb (RP159-1)
This antibody has been tested in immunohistochemistry, analyzed by an anatomic pathologist and validated for use in IHC applications against formalin-fixed, paraffin-embedded human tissues. The image shows the localization of the antibody as the precipitated red signal, with a hematoxylin purple nuclear counterstain.
1: Human RPS3.
2: HepG2 cell lysate (70μg).
3: HEK 293 cell lysate (70μg).
Product Details | |
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Synonyms | 40S Ribosomal Protein S3; IMR-90 Ribosomal Protein S3; RPS3 |
Product Type | Monoclonal Antibody |
Properties | |
Clone | RP159-1 |
Isotype | Mouse IgG1κ |
Immunogen/Antigen | Recombinant human ribosomal protein S3. |
Application |
ELISA: (direct or indirect: 1:500-1:5'000) |
Crossreactivity | Human |
Specificity |
Recognizes human ribosomal protein S3. Detects a band of ~32kDa by Western blot. |
Purity Detail | Protein G-affinity purified. |
Concentration | 1mg/ml |
Formulation | Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. |
Isotype Negative Control | |
Shipping and Handling | |
Shipping | BLUE ICE |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice |
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. |
Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
RpS3 is a component of the 40S ribosomal subunit and is an an essential but previously unkown subunit of NF-κB involved in the regulation of key genes in rapid cellular activation responses. RpS3 interacts with nm23-H1. The expression of rpS3 reduces the secretion of MMP-9 and the invasive metastatic potential in HT1080 cells. The phosphorylated ERK is reduced by the expression of rpS3.