AdipoGen Life Sciences

anti-FGF-19 (human), mAb (FG369-1)

CHF 190.00
In stock
AG-20A-0066-C05050 µgCHF 190.00
AG-20A-0066-C100100 µgCHF 320.00
More Information
Product Details
Synonyms Fibroblast Growth Factor 19
Product Type Monoclonal Antibody
Properties
Clone FG369-1
Isotype Mouse IgG1κ
Immunogen/Antigen Recombinant human FGF-19.
Application

ELISA: (direct or indirect: 1:2'000-1:5'000)
Immunohistochemistry: (paraffin sections, 15µg/ml)
Western blot: (1:2'000-1:5'000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature).
Optimal conditions should be determined individually for each application.

Note: Tested on recombinant proteins and/or target-protein transfected cell lines in ELISA, Western Blot and/or FACS.

Crossreactivity Human
Specificity

Recognizes human FGF-19. Detects a band of ~25kDa by Western blot.

Purity Detail Protein G-affinity purified.
Concentration 1mg/ml
Formulation Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Isotype Negative Control

Mouse IgG1 Isotype Control

Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice After opening, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

FGF-19 is involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. FGF-19 plays an important role in brain development during embryogenesis. FGF-19 binds only to FGF receptor 4 (FGFR4). Activity requires the presence of KLB.

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