anti-BAFF-R (human), mAb (HuBR9.1) (ATTO 488)
BJAB and Jurkat cells were stained with A) 20 μg /ml (and 2-fold dilutions) and B) 2μg /ml of anti-BAFF-R (human), mAb (HuBR9.1) in 50 μl FACS buffer (PBS, 5% fetal calf serum, 0.02% azide), revealed with anti-mouse-PE (1/200) and then analyzed by flow cytometry.
|Synonyms||BAFF Receptor; BR3; BlySR3; CD268; TNFRSF13C|
|Product Type||Monoclonal Antibody|
|Source/Host||Purified from concentrated hybridoma tissue culture supernatant.|
|Immunogen/Antigen||Cells transfected with human BAFF-R.|
Recognizes human BAFF-R.
|Purity Detail||Protein G-affinity purified.|
|Formulation||Liquid. In PBS containing 0.02% sodium azide.|
|Isotype Negative Control|
|Other Product Data||
New ATTO-fluorescent antibodies show increased photostability, outstanding brightness and intense signals. ATTO dyes are thermally stable, resistant to environmental changes and show no significant isomerization.
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||+4°C|
Do not freeze.
Protect from light.
Keep conjugated formats at +4°C.
Stable for at least 1 year after receipt when stored at +4°C.
|Product Specification Sheet|
Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF-R signaling is essential for B cell development, survival and humoral immune responses.
- BAFF-R expression correlates with positive selection of immature B cells: R. Tussiwand, et al.; Eur. J. Immunol. 42, 206 (2012)
- A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors: M. Vigolo, et al.; Nat. Commun. 9, 1199 (2018)