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AdipoGen Life Sciences
anti-VEGF-A (human), mAb (3(6D3))
Product Details | |
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Synonyms | Vascular Endothelial Growth Factor-A; VPF |
Product Type | Monoclonal Antibody |
Properties | |
Clone | 3(6D3) |
Isotype | Mouse IgG1 |
Immunogen/Antigen | Recombinant human VEGF 165. |
Application |
ELISA: (1-15μg/ml) |
Crossreactivity | Human |
Purity | Protein G purified. |
Purity Detail | Protein G purified. |
Formulation | Lyophilized from a buffer containing Trehalose, Na-Phosphate and Polysorbat 20. |
Reconstitution | Centrifuge vial prior to opening. Reconstitute with sterile water to a concentration of 0.1-1.0mg/ml. |
Isotype Negative Control | |
Shipping and Handling | |
Shipping | BLUE ICE |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice |
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. |
Use/Stability | Stable for at least 6 months after receipt when stored at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
Human vascular endothelial growth factor (VEGF 165) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. VEGF-A is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. In addition to its action as a mitogen it is a potent vascular permeability factor (VPF) in vivo. It is also a chemoattractant molecule for monocytes and endothelial cells. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.