AdipoGen Life Sciences

VEGF-C (rat) (rec.) (His)

CHF 195.00
In stock
AG-40T-0048-C0055 µgCHF 195.00
AG-40T-0048-C02020 µgCHF 395.00
More Information
Product Details
Synonyms Vascular Endothelial Growth Factor C; VRP; Flt4-L
Product Type Protein
Properties
Source/Host Sf9 cells
Sequence Rat VEGF-C (127aa) is fused at the C-terminus to a His-tag.
Crossreactivity Rat
MW ~15-20kDa
Purity ≥90% (SDS-PAGE)
Reconstitution Soluble in water and most aqueous buffers. Reconstitute with PBS or medium to a concentration not lower than 50μg/ml.
Formulation Lyophilized.
Other Product Data UniProt link O35757: VEGF-C (rat)
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
Centrifuge lyophilized vial before opening and reconstitution.
Use/Stability Stable for at least 6 months after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

VEGF-C forms primarily non-covalently linked dimers. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. It binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. It is a growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. It is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. It is also a mitogen for vascular endothelial cells.

Product References
  1. Effects of VEGFR-3 phosphorylation inhibitor on lymph node metastasis in an orthotopic diffuse-type gastric carcinoma model: M. Yashiro, et al.; Br. J. Cancer 101, 1100 (2009) 
  2. Vascular endothelial growth factor receptor 3 directly regulates murine neurogenesis: CF. Calvo, et al.; Genes Dev. 25, 831 (2011)
© 2017 Adipogen Life Sciences. Pictures: © 2012 Martin Oeggerli. All Rights Reserved.