Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
AdipoGen Life Sciences
VEGF-C (rat) (rec.) (His)
195
CHF
CHF 195.00
In stock
AG-40T-0048-C0055 µgCHF 195.00
AG-40T-0048-C02020 µgCHF 395.00
| Product Details | |
|---|---|
| Synonyms | Vascular Endothelial Growth Factor C; VRP; Flt4-L |
| Product Type | Protein |
| Properties | |
| Source/Host | Sf9 cells |
| Sequence | Rat VEGF-C (127aa) is fused at the C-terminus to a His-tag. |
| Crossreactivity | Rat |
| MW | ~15-20kDa |
| Purity | ≥90% (SDS-PAGE) |
| Reconstitution | Soluble in water and most aqueous buffers. Reconstitute with PBS or medium to a concentration not lower than 50μg/ml. |
| Formulation | Lyophilized. |
| Other Product Data | UniProt link O35757: VEGF-C (rat) |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. |
| Use/Stability | Stable for at least 6 months after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
VEGF-C forms primarily non-covalently linked dimers. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. It binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. It is a growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. It is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. It is also a mitogen for vascular endothelial cells.
Product References
- Effects of VEGFR-3 phosphorylation inhibitor on lymph node metastasis in an orthotopic diffuse-type gastric carcinoma model: M. Yashiro, et al.; Br. J. Cancer 101, 1100 (2009)
- Vascular endothelial growth factor receptor 3 directly regulates murine neurogenesis: CF. Calvo, et al.; Genes Dev. 25, 831 (2011)
Related Products
