AdipoGen Life Sciences

anti-DNER (human), pAb

As low as CHF 190.00

In stock

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AG-25A-0102-C100100 µgCHF 190.00

Figure 1: Western blot analysis using anti-DNER (human), pAb (Prod. No. AG-25A-0102) at 1:4'000 dilution.
1: Human DNER (ED) (FLAG^®-tagged).
2: Human DNER (ED) Fc-protein.
3: Human DLL1 (His-tagged).
4: Human DLL4 (His-tagged).
5: Human DLK1 (His-tagged).
6: Human Jagged-1 (His-tagged) (negative control).
7: Human FGF-23 Fc-protein (negative control).

Specifications / Handling

More Information
Product Details
Synonyms	BET; UNQ262/PRO299; Delta and Notch-like Epidermal Growth Factor-related Receptor
Product Type	Polyclonal Antibody
Properties
Source/Host	Rabbit
Immunogen/Antigen	Recombinant human DNER (ectodomain).
Application	ELISA: (direct and indirect: 1:2’000-1:5’000) Western Blot: (1:2’000-1:5’000 using ECL; suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk; suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application. Note: Tested on recombinant proteins and/or target-protein transfected cell lines in ELISA, Western Blot and/or FACS.
Crossreactivity	Human
Specificity	Recognizes human DNER (ED). Detects a band of ~98kDa by Western blot.
Purity Detail	Protein A-affinity purified.
Concentration	1mg/ml
Formulation	Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Isotype Negative Control	Rabbit IgG
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Use/Stability	Stable for at least 6 months after receipt when stored at -20°C.
Documents
Safety Data Sheet	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Scientific Background Information

Product Description

DNER is an activator of the Notch1 pathway. It mediates neuron-glia interaction during astrocytogenesis.

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