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AdipoGen Life Sciences
anti-Adiponectin Receptor 1 (human), pAb (AL238)
190
CHF
CHF 190.00
In stock
AG-25B-0010-R100100 µlCHF 190.00
Figure 1: Immunohistochemical staining (paraffin embedded) of human adipose tissue using anti-Adiponectin Receptor 1 (human), pAb (AL238) (Prod. No. AG-25B-0010).
| Product Details | |
|---|---|
| Synonyms | AdipoR1; CGI-45 |
| Product Type | Polyclonal Antibody |
| Properties | |
| Source/Host | Rabbit |
| Immunogen/Antigen | Synthetic peptide corresponding to aa 2-36 (S2SHKGSVVAQGNGAPASNREADTVELAEL GPLLEE36) of human adiponectin receptor 1. |
| Application |
Immunohistochemistry: (paraffin sections: 1:100) Note: Tested on recombinant proteins and/or target-protein transfected cell lines in ELISA, Western Blot and/or FACS. |
| Crossreactivity | Human |
| Specificity |
Recognizes human adiponectin receptor 1. |
| Formulation | Liquid. Neat serum containing 0.02% sodium azide. |
| Isotype Negative Control | |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
AdipoR1 is a receptor for globular and full-length adiponectin, an essential hormone secreted by adipocytes that acts as an antidiabetic. AdipoR1 is probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. It mediates increased AMPK, PPAR-α ligand activity, fatty acid oxidation and glucose uptake by adiponectin. It is a high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin. It is widely expressed.
Product References
- Fibrosis is associated with adiponectin resistance in chronic hepatitis C virus infection: S. Corbetta, et al.; Eur. J. Clin. Invest. 41, 898 (2011)
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