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AdipoGen Life Sciences
anti-Repetin, pAb (AF646)
240
CHF
CHF 240.00
In stock
AG-25B-0017-C05050 µgCHF 240.00
Figure 1: Immunohistochemical staining of repetin using anti-Repetin, pAb (AF646) (Prod. No. AG-25B-0017) and FITC-labeled anti-rabbit IgG antibody on frozen section of human skin (A), human foreskin (B), human tongue (C and D) and human hair follicles (E and F).
Figure 2: Western blot analysis of repetin expression in cytosolic (lane 1), membrane (lane 2) and cytoskeletal (lane 3) extracts from suspension-induced human keratinocytes (A) and human foreskin biopsy (B) using anti-Repetin, pAb (AF646) (Prod. No. AG-25B-0017).
| Product Details | |
|---|---|
| Product Type | Polyclonal Antibody |
| Properties | |
| Source/Host | Rabbit |
| Immunogen/Antigen | Synthetic peptide corresponding to aa 570-584 (H570YGQTDRQGQSSHYI584) of human repetin. |
| Application |
Immunohistochemistry: (frozen sections: 1:250-1:500) |
| Crossreactivity |
Human Mouse |
| Specificity |
Recognizes human and mouse repetin. Detects a band of ~100kDa by Western blot. |
| Concentration | 1 mg/ml |
| Formulation | Liquid. In PBS containing 0.5% BSA and 0.005% sodium azide and 50% glycerol. |
| Isotype Negative Control | |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Repetin is a late epidermal differentiation marker. Repetin is involved in the formation of the cornified cell envelope. It is a multifunctional epidermal matrix protein, which reversibly binds to calcium. Its expression is scattered in the normal epidermis but strong in the acrosyringium, the inner hair root sheat and in the filiform papilli of the tongue.
Product References
- Isolation and Characterization of Human Repetin, a Member of the Fused Gene Family of the Epidermal Differentiation Complex: M. Huber, et al.; J. Invest. Dermatol. 124, 998 (2005)