Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
AdipoGen Life Sciences
Resistin (mouse) (rec.)
380
CHF
CHF 380.00
In stock
AG-40A-0011-C05050 µgCHF 380.00
| Product Details | |
|---|---|
| Synonyms | FIZZ3; Found in Inflammatory Zone 3; ADSF; Adipose Tissue-Specific Secretory Factor |
| Product Type | Protein |
| Properties | |
| Source/Host | HEK 293 cells |
| Sequence | Mouse resistin (aa 21-114) is fused at the N-terminus to a FLAG®-tag. |
| Crossreactivity | Mouse |
| Application | Has been shown to be a fully-functional ligand for decorin [1]. |
| MW | ~15kDa (SDS-PAGE) |
| Purity | ≥90% (SDS-PAGE) |
| Endotoxin Content | <0.1EU/μg purified protein (LAL test; Lonza). |
| Concentration | 0.4mg/ml |
| Formulation | Liquid. 0.2μm-filtered solution in PBS, pH 7.2. |
| Other Product Data |
UniProt link Q99P87: Resistin (mouse) (precursor) FLAG is a registered trademark of Sigma-Aldrich Co. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap. |
| Use/Stability |
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELM-α/FIZZ 1 and RELM-β/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
Product References
- An Isoform of Decorin Is a Resistin Receptor on the Surface of Adipose Progenitor Cells: A.C. Daquinag, et al.; Cell Stem Cell 9, 74 (2011)
Related Products
