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AdipoGen Life Sciences
RBP4 (rat) (rec.)
180
CHF
CHF 180.00
In stock
AG-40A-0049-C01010 µgCHF 180.00
AG-40A-0049-C05050 µgCHF 370.00
| Product Details | |
|---|---|
| Synonyms | Retinol Binding Protein 4 |
| Product Type | Protein |
| Properties | |
| Source/Host | HEK 293 cells |
| Sequence |
Rat RBP4 (aa 19-201) is fused at the N-terminus to a FLAG®-tag. |
| Crossreactivity | Rat |
| MW | ~23kDa (SDS-PAGE) |
| Purity | ≥90% (SDS-PAGE) |
| Endotoxin Content | <0.1EU/μg purified protein (LAL test; Lonza). |
| Concentration | Lot dependent. |
| Formulation | Liquid. 0.2μm-filtered solution in PBS, pH 7.2. |
| Other Product Data |
UniProt link P04916: RBP4 (rat) [Precursor] FLAG is a registered trademark of Sigma-Aldrich Co. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap. |
| Use/Stability |
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Retinol binding protein 4 (RBP4; RBP) is a 21kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity, and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.
Product References
- Retinol-binding protein 4 and peroxisome proliferator-activated receptor-γ in steatotic liver transplantation: A. Casillas-Ramirez, et al.; J. Pharmacol. Exp. Ther. 338, 143 (2011)
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