AdipoGen Life Sciences

Omentin (human) (rec.)

As low as CHF 220.00
In stock
Only %1 left
AG-40B-0042-C01010 µgCHF 220.00
AG-40B-0042-30103 x 10 µgCHF 455.00

Specifications / Handling

More Information
Product Details
Synonyms Galactofuranose-binding Lectin; Intestinal Lactoferrin Receptor; Intelectin-1; ITLN1; Endothelial Lectin HL-1; Omentin 1
Product Type Protein
Properties
Source/Host CHO cells
Sequence

Human omentin (aa 17-313) is fused at the N-terminus to a FLAG®-tag.

Crossreactivity Human
Biological Activity

Enhances glucose transport mediated by insulin.

MW ~38kDa
Purity ≥95% (SDS-PAGE)
Endotoxin Content <0.1EU/μg purified protein (LAL test; Lonza).
Concentration 0.1mg/ml after reconstitution.
Reconstitution Reconstitute with 100μl sterile water.
Formulation Lyophilized. Contains PBS.
Other Product Data

UniProt link Q8WWA0: Omentin (human) [Precursor]

FLAG is a registered trademark of Sigma-Aldrich Co.

Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
Centrifuge lyophilized vial before opening and reconstitution.
PBS containing at least 0.1% BSA should be used for further dilutions.
Use/Stability Stable for at least 6 months after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Download PDF Download PDF
Product Specification Sheet
Datasheet Download PDF Download PDF

Scientific Background Information

Product Description

Omentin (Intelectin-1) is highly expressed in omental adipose tissue, small intestine and various other tissues. Omentin has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases AKT phosphorylation in the absence and presence of insulin. It was suggested to play a role in the defense system against microorganisms by recognizing carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues.

Product-specific References
  1. Ginsenoside Rd promotes omentin secretion in adipose through TBK1-AMPK to improve mitochondrial biogenesis via WNT5A/Ca2+ pathways in heart failure: S. Wan, et al.; Redox Biol. 60,  102610 (2023)
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