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AdipoGen Life Sciences
Omentin (human) (rec.)
220
CHF
CHF 220.00
In stock
AG-40B-0042-C01010 µgCHF 220.00
AG-40B-0042-30103 x 10 µgCHF 455.00
| Product Details | |
|---|---|
| Synonyms | Galactofuranose-binding Lectin; Intestinal Lactoferrin Receptor; Intelectin-1; ITLN1; Endothelial Lectin HL-1; Omentin 1 |
| Product Type | Protein |
| Properties | |
| Source/Host | CHO cells |
| Sequence |
Human omentin (aa 17-313) is fused at the N-terminus to a FLAG®-tag. |
| Crossreactivity | Human |
| Biological Activity |
Enhances glucose transport mediated by insulin. |
| MW | ~38kDa |
| Purity | ≥95% (SDS-PAGE) |
| Endotoxin Content | <0.1EU/μg purified protein (LAL test; Lonza). |
| Concentration | 0.1mg/ml after reconstitution. |
| Reconstitution | Reconstitute with 100μl sterile water. |
| Formulation | Lyophilized. Contains PBS. |
| Other Product Data |
UniProt link Q8WWA0: Omentin (human) [Precursor] FLAG is a registered trademark of Sigma-Aldrich Co. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1% BSA should be used for further dilutions. |
| Use/Stability |
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Omentin (Intelectin-1) is highly expressed in omental adipose tissue, small intestine and various other tissues. Omentin has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases AKT phosphorylation in the absence and presence of insulin. It was suggested to play a role in the defense system against microorganisms by recognizing carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues.
Product References
- Ginsenoside Rd promotes omentin secretion in adipose through TBK1-AMPK to improve mitochondrial biogenesis via WNT5A/Ca2+ pathways in heart failure: S. Wan, et al.; Redox Biol. 60, 102610 (2023)
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