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AdipoGen Life Sciences
Angiocidin (human) (rec.)
385
CHF
CHF 385.00
In stock
AG-40B-0061-C01010 µgCHF 385.00
| Product Details | |
|---|---|
| Synonyms | PSMD4; 26S Proteasome Regulatory Subunit S5A; Rpn10; Multiubiquitin Chain-binding Protein; Antisecretory Factor 1; 26S Proteasome Non-ATPase Regulatory Subunit 4 |
| Product Type | Protein |
| Properties | |
| Source/Host | E. coli |
| Sequence | Human angiocidin (aa 2-377) is untagged. |
| Crossreactivity | Human |
| MW | ~50kDa (SDS-PAGE) |
| Purity | ≥95% (SDS-PAGE) |
| Endotoxin Content | <0.1EU/μg purified protein (LAL test; Lonza). |
| Concentration | 0.1mg/ml after reconstitution. |
| Reconstitution | Reconstitute with 100μl sterile water. |
| Formulation | Lyophilized. Contains PBS. |
| Other Product Data | UniProt link P55036: Angiocidin (human) |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1% BSA should be used for further dilutions. |
| Use/Stability |
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Angiocidin shows sequence similarity with proteasome components and is also being referred to as 26A proteasome regulatory subunit S5A. Angiocidin shows both matrix and cytoplasmic distribution. It binds to thrombospondin-1 and α2β1 integrin, and it inhibits tumor progression and angiogenesis. Angiocidin is expressed in various types of cancer, such as hepatocellular carcinoma, prostate, lung, bladder, and melanoma cancers.