AdipoGen Life Sciences

BCMA (mouse):Fc (human) (rec.)

CHF 240.00

In stock

AG-40B-0076-C05050 µgCHF 240.00

AG-40B-0076-30503 x 50 µgCHF 480.00

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Product Details
Synonyms	B Cell Maturation Protein; CD269; TNFRSF17
Product Type	Protein
Properties
Source/Host	HEK 293 cells
Sequence	The extracellular domain of mouse BCMA (aa 1-46) is fused at the C-terminus to the Fc portion of human IgG1.
Crossreactivity	Human Mouse
Specificity	Binds mouse and human BAFF and APRIL.
Biological Activity	Blocks the binding of mouse BAFF and human APRIL to their receptors BCMA and TACI.
MW	~35kDa (SDS-PAGE)
Purity	≥95% (SDS-PAGE)
Endotoxin Content	<0.01EU/μg purified protein (LAL test; Lonza).
Concentration	1mg/ml after reconstitution.
Reconstitution	Reconstitute with 50μl sterile water.
Formulation	Lyophilized. Contains PBS.
Protein Negative Control	Fc (human) IgG1 Control (rec.)
Other Product Data	UniProt link O88472: BCMA (mouse)
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1% BSA should be used for further dilutions.
Use/Stability	Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

BCMA is a receptor for BAFF and APRIL. It promotes B cell survival and plays a role in the regulation of humoral immunity. It's downstream signaling is dependent on NF-κB and JNK.

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