AdipoGen Life Sciences

BCMA (mouse):Fc (human) (rec.)

CHF 240.00
In stock
AG-40B-0076-C05050 µgCHF 240.00
AG-40B-0076-30503 x 50 µgCHF 480.00
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Product Details
Synonyms B Cell Maturation Protein; CD269; TNFRSF17
Product Type Protein
Properties
Source/Host HEK 293 cells
Sequence

The extracellular domain of mouse BCMA (aa 1-46) is fused at the C-terminus to the Fc portion of human IgG1.

Crossreactivity Human
Mouse
Specificity

Binds mouse and human BAFF and APRIL.

Biological Activity

Blocks the binding of mouse BAFF and human APRIL to their receptors BCMA and TACI.

MW ~35kDa (SDS-PAGE)
Purity ≥95% (SDS-PAGE)
Endotoxin Content <0.01EU/μg purified protein (LAL test; Lonza).
Concentration 1mg/ml after reconstitution.
Reconstitution Reconstitute with 50μl sterile water.
Formulation Lyophilized. Contains PBS.
Protein Negative Control

Fc (human) IgG1 Control (rec.)

Other Product Data

UniProt link O88472: BCMA (mouse)

Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
Centrifuge lyophilized vial before opening and reconstitution.
PBS containing at least 0.1% BSA should be used for further dilutions.
Use/Stability Stable for at least 6 months after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

BCMA is a receptor for BAFF and APRIL. It promotes B cell survival and plays a role in the regulation of humoral immunity. It's downstream signaling is dependent on NF-κB and JNK.

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