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AdipoGen Life Sciences
FGF-2 (human) (rec.)
150
CHF
CHF 150.00
In stock
AG-40T-0040-C01010 µgCHF 150.00
AG-40T-0040-C05050 µgCHF 270.00
| Product Details | |
|---|---|
| Synonyms | Basic Fibroblast Growth Factor; bFGF; Heparin Binding Growth Factor-2; HBGF-2 |
| Product Type | Protein |
| Properties | |
| Source/Host | E. coli |
| Sequence | Human FGF-2 (153aa). |
| Crossreactivity | Human |
| Biological Activity | The ED50 for stimulation of cell proliferation in human umbilical vein endothelial cells by human FGF-2 (basic) has been determined to be in the range of 0.1-2 ng/ml. |
| MW | ~16.5kDa |
| Purity | ≥98% (SDS-PAGE) |
| Endotoxin Content | <0.1ng/µg protein. |
| Reconstitution | Reconstitute with sterile water containing at least 0.1% human or bovine serum albumin to a concentration not lower than 50µg/ml. |
| Formulation | Lyophilized. Contains PBS. |
| Other Product Data | UniProt link P09038: FGF-2 (human) |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. |
| Use/Stability | Stable for at least 6 months after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
FGF-2 plays an important role in the regulation of angiogenesis, cell survival, cell division, wound healing and tissue repair, embryonic development, cell differentiation and cell migration, neuronal function and neural degeneration. It functions as potent mitogen in vitro.
Product References
- Loss of Akt activity increases circulating soluble endoglin release in preeclampsia: identification of inter-dependency between Akt-1 and heme oxygenase-1: M.J. Cudmore, et al.; Europ. Heart J. 33, 1150 (2012)
- Endothelial Heparan Sulfate 6-O-sulfation Levels Regulate Angiogenic Responses of Endothelial Cells to FGF2 and VEGF: C. Ferreras, et al.; J. Biol. Chem. 287, 36132 (2012)
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