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AdipoGen Life Sciences
RELM-β (human) Matched Pair Detection Set
Product Details | |
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Synonyms | HXCP2; Resistin-like Molecule-β; FIZZ2 |
Product Type | Kit |
Properties | |
Application Set | Quantitative ELISA |
Specificity | Does not cross-react with human adiponectin, mouse adiponectin, human RBP4, human Nampt, human vaspin, human GPX3, human ANGPTL3, human progranulin, human leptin, human resistin, human IL-33, human sirtuin 1, human clusterin, mouse resistin, human FABP4. |
Crossreactivity | Human |
Quantity | Contains sufficient materials to run ELISAs on 5 x 96-well plates. |
Sensitivity | 10pg/ml |
Range | 0.016 to 1ng/ml |
Assay Type | Sandwich |
Detection Type | Colorimetric |
Kit Contains |
1 vial standard protein (1μg) (lyophilized) [STD] 1 vial coating antibody (300μl) [COAT] 1 vial detection antibody (120μl) [DET] 1 vial anti-rabbit IgG-HRP (8μg) (lyophilized) [HRP] |
Shipping and Handling | |
Shipping | BLUE ICE |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Avoid freeze/thaw cycles. |
Use/Stability | Stable for at least 6 months after receipt when stored at +4°C. |
Documents | |
Manual | Download PDF |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
RELM-β is a 19kDa disulfide-linked homodimeric protein expressed in the epithelium of the colon and small bowel. RELM-β has been suggested to play a regulatory role during inflammation and may also act to establish links among adipose tissue, the intestine and the liver. Interestingly, the molecular structure of RELM-β is highly homologous to that of the adipose-derived cytokine resistin.
The specific and sensitive RELM-β Matched Pair Detection Set might detect RELM-β in serum of gut-inflamed patients (e.g. inflammatory bowel diseases, Crohn disease and ulcerative colitis). Natural levels of RELM-β were seen in stool, but were not detectable in the serum or other cell culture models of healthy human patients. Further testing are ongoing.