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AdipoGen Life Sciences
n-Octyl-β-D-thioglucopyranoside (ultrapure)
65
CHF
CHF 65.00
In stock
AG-CC1-0005-G0011 gCHF 65.00
AG-CC1-0005-G0055 gCHF 260.00
| Product Details | |
|---|---|
| Synonyms | OTG; Octylthioglucoside; n-Octyl 1-thio-β-D-glucopyranoside |
| Product Type | Chemical |
| Properties | |
| Formula |
C14H28O5S |
| MW | 308.4 |
| CAS | 85618-21-9 |
| Purity Chemicals |
≥99% (HPLC) [α-Isomer <0.01% (HPLC)] [n-Octanthiol <0.001% (HPLC)] |
| Appearance | White powder. |
| Solubility | Soluble in water or methanol. |
| InChi Key | CGVLVOOFCGWBCS-RGDJUOJXSA-N |
| Smiles | CCCCCCCCSC1OC(CO)C(O)C(O)C1O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Hygroscopic. Protect from light and moisture. |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Non-ionic detergent.
- For functional solubilization, purification and crystallography of membrane proteins.
- The thioether linkage makes it resistant to degradation by beta-glucosidase enzymes.
- For the stabilization and activation of enzymes.
- Used for cell lysis experiments.
Product References
- Use of n-octyl-beta-D-thioglucoside, a new nonionic detergent, for solubilization and reconstitution of membrane proteins: T. Tsuchiya & S. Saito; J. Biochem. 96, 1593 (1984)
- Characteristics of n-octyl beta-D-thioglucopyranoside, a new non-ionic detergent useful for membrane biochemistry: S. Saito & T. Tsuchiya; Biochem. J. 222, 829 (1984)
- Use of octyl beta-thioglucopyranoside in two-dimensional crystallization of membrane proteins: M. Chami, et al.; J. Struct. Biol. 133, 64 (2001)
- Surface Activity, Micelle Formation, and Growth of n-Octyl-β-d-Thioglucopyranoside in Aqueous Solutions at Different Temperatures: J.A. Molina-Bolivar, et al.; J. Phys. Chem. B 108, 12813 (2004)
- Use of n-Octyl-β-D-thioglucopyranoside in the isolation of a bacterial membrane protein: an improved method for immunological applications.: J.M. Peula-Garcia, et al.; J. Surface Sci. Technol. 22, 141 (2006)
- Development and crystallization of a minimal thermostabilised G protein-coupled receptor: T. Warne, et al.; Protein Expr. Purif. 65, 204 (2009)
- Solubilization and structural stability of bacteriorhodopsin with a mild nonionic detergent, n-Octyl-beta-thioglucoside: A. Asada, & M. Sonoyama; Biosci. Biotechnol. Biochem. 75, 376 (2011)
- Characterization of mixed non-ionic surfactants n-octyl-beta-D-thioglucoside and octaethylene-glycol monododecyl ether: micellization and microstructure: C.C. Ruiz & J.A. Molina-Bolivar; J. Colloid. Interface Sci. 361, 178 (2011)
- Mass spectrometry of intact membrane protein complexes: A. Laganowsky, et al.; Nat. Protocols 8, 639 (2013)
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