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AdipoGen Life Sciences
n-Dodecyl-β-D-maltoside (high purity)
As low as
70
CHF
CHF 70.00
In stock
Only %1 left
AG-CC1-0010-G0011 gCHF 70.00
AG-CC1-0010-G0055 gCHF 195.00
AG-CC1-0010-G02525 gCHF 720.00
Specifications / Handling
| Product Details | |
|---|---|
| Synonyms | DDM; n-Dodecyl-β-maltoside; Lauryl-β-maltoside; Dodecyl-β-D-maltopyranoside |
| Product Type | Chemical |
| Properties | |
| Formula |
C24H46O11 |
| MW | 510.6 |
| CAS | 69227-93-6 |
| Purity Chemicals |
≥99% (HPLC) [α-Anomer <2.0% (NMR)] [n-Dodecanol <0.005% (HPLC)] |
| Appearance | White powder. |
| Solubility | Soluble in water or 100% ethanol. |
| InChi Key | NLEBIOOXCVAHBD-QKMCSOCLSA-N |
| Smiles | CCCCCCCCCCCCOC1OC(CO)C(OC2OC(CO)C(O)C(O)C2O)C(O)C1O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Hygroscopic. Protect from light and moisture. |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Scientific Background Information
Product Description
- Water-soluble non-ionic detergent with a hydrophilic maltose head and a hydrophobic long chain alkyl tail. It is considered a gentle detergent that is more efficient than other detergents.
- For functional solubilization and purification of membrane proteins. It helps to retain the native conformation and activity of membrane-associated proteins and facilitates the reforming of these proteins after denaturation.
- For the stabilization and activation of enzymes.
- The critical micelle concentration of DDM is approx. 0.18 mM in water, decreases in the presence of sodium chloride or sucrose and increases in urea.
Product-specific References
- Synthesis and properties of some α-D-alkyl glucosides and mannosides: apparent molal volumes and solubilization of nitrobenzene in water at 25°C: G.M. Brown, et al.; Can. J. Chem. 48, 2525 (1970)
- Detergent-mediated reconstitution of membrane proteins: J. Knol, et al.; Biochem. 37, 16410 (1998)
- The vesicle-to-micelle transition of phosphatidylcholine vesicles induced by nonionic detergents: Effects of sodium chloride, sucrose and urea: A. Walter, et al.; Biochim. Biophys. Acta 1508, 20 (2000)
- Macromolecular Crystallography Protocols: S. Doublie; Methods Mol. Biol. 363, (2007)
- Detergents for the stabilization and crystallization of membrane proteins: G.G. Prive; Methods 41, 388 (2007)
- The use of detergents to purify membrane proteins; T. Arnold & D. Linke; Curr. Protoc. Protein Sci. Chapter 4: Unit 4.8.1-4.8.30 (2008)
- Expression, purification and in vitro functional reconstitution of the chemokine receptor CCR1: S.J. Allen, et al.; Prot. Expr. Purif. 66, 73 (2009)
- Structuring detergents for extracting and stabilizing functional membrane proteins: R. Matar-Merheb, et al.; PLoS One 6, e18036 (2011)
- Efficiency of detergents at maintaining membrane protein structures in their biologically relevant forms: D.V. Tulumello & C.M. Deber; Biochim. Biophys. Acta. 1818, 1351 (2012)
- High-throughput stability screening for detergent-solubilized membrane proteins: V. Kotov, et al.; Sci. Rep. 9, 10379 (2019)
Related Products
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n-Dodecyl-α-D-maltoside (ultrapure) AG-CC1-0006 -
n-Dodecyl-β-D-maltoside (ultrapure) AG-CC1-0004
