AdipoGen Life Sciences

Lariatin A

CHF 150.00
In stock
AG-CN2-0120-C250250 µgCHF 150.00
AG-CN2-0120-M0011 mgCHF 450.00
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Product Details
Synonyms GSQLVYREWVGHSNVIKP; H-Gly-Ser-Gln-Leu-Val-Tyr-Arg-Glu-Trp-Val-Gly-His-Ser-Asn-Val-Ile-Lys-Pro-OH
Product Type Chemical
Properties
Formula

C94H143N27O25

MW 2051.4
CAS 732286-09-8
Source/Host Chemicals Isolated from Rhodococcus jostii.
Purity Chemicals ≥95% (HPLC)
Appearance Off-white solid.
Solubility Soluble in methanol or water.
InChi Key ZYWDOXCVVHITIW-KBACZRJDSA-N
Smiles [H]N([C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(O)=O)C(=O)C1CCC(=O)N([H])CC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N([H])[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CC=C(O)C=C2)C(=O)N[C@H](CCCNC(N)=N)C(=O)N1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Use/Stability Stable for at least 3 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Peptide with lasso structure.
  • Antimycobacterial.
Product References
  1. Lariatins, antimycobacterial peptides produced by Rhodococcus sp. K01-B0171, have a lasso structure: M. Iwatsuki, et al.; JACS 128, 7486 (2006)
  2. Lariatins, novel anti-mycobacterial peptides with a lasso structure, produced by Rhodococcus jostii K01-B0171: M. Iwatsuki, et al.; J. Antibiot. (Tokyo) 60, 357 (2007)
  3. Lys17 in the 'lasso' peptide lariatin A is responsible for anti-mycobacterial activity: M. Iwatsuki, et al.; Bioorg. Med. Chem. Lett. 19, 2888 (2009)
  4. Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B0171: J. Inokoshi, et al.; Appl. Microbiol. Biotechnol. 95, 451 (2012)
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