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AdipoGen Life Sciences
Lariatin A
150
CHF
CHF 150.00
In stock
AG-CN2-0120-C250250 µgCHF 150.00
AG-CN2-0120-M0011 mgCHF 450.00
Product Details | |
---|---|
Synonyms | GSQLVYREWVGHSNVIKP; H-Gly-Ser-Gln-Leu-Val-Tyr-Arg-Glu-Trp-Val-Gly-His-Ser-Asn-Val-Ile-Lys-Pro-OH |
Product Type | Chemical |
Properties | |
Formula |
C94H143N27O25 |
MW | 2051.4 |
CAS | 732286-09-8 |
Source/Host Chemicals | Isolated from Rhodococcus jostii. |
Purity Chemicals | ≥95% (HPLC) |
Appearance | Off-white solid. |
Solubility | Soluble in methanol or water. |
InChi Key | ZYWDOXCVVHITIW-KBACZRJDSA-N |
Smiles | [H]N([C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(O)=O)C(=O)C1CCC(=O)N([H])CC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N([H])[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CC=C(O)C=C2)C(=O)N[C@H](CCCNC(N)=N)C(=O)N1 |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Keep cool and dry. |
Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
Description
- Peptide with lasso structure.
- Antimycobacterial.
Product References
- Lariatins, antimycobacterial peptides produced by Rhodococcus sp. K01-B0171, have a lasso structure: M. Iwatsuki, et al.; JACS 128, 7486 (2006)
- Lariatins, novel anti-mycobacterial peptides with a lasso structure, produced by Rhodococcus jostii K01-B0171: M. Iwatsuki, et al.; J. Antibiot. (Tokyo) 60, 357 (2007)
- Lys17 in the 'lasso' peptide lariatin A is responsible for anti-mycobacterial activity: M. Iwatsuki, et al.; Bioorg. Med. Chem. Lett. 19, 2888 (2009)
- Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B0171: J. Inokoshi, et al.; Appl. Microbiol. Biotechnol. 95, 451 (2012)