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Cyclopenin

CHF 150.00
In stock
AG-CN2-0134-M0011 mgCHF 150.00
AG-CN2-0134-M0055 mgCHF 600.00
More Information
Product Details
Synonyms NSC 114538
Product Type Chemical
Properties
Formula

C17H14N2O3

MW 294.3
CAS 19553-26-5 and 20007-87-8
Source/Host Chemicals Isolated from Penicillium sp.
Purity Chemicals ≥98% (HPLC)
Appearance White to slightly pink powder.
Solubility Soluble in DMSO, methanol, chloroform or ethyl acetate. Insoluble in water or hexane.
Other Product Data

Note: Cyclopenin is an intermediate in the biosynthesis of the viridicatins.

InChi Key APLKWZASYUZSBL-XPCCGILXSA-N
Smiles CN1C(=O)C2=C(NC(=O)C11O[C@@H]1C1=CC=CC=C1)C=CC=C2
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Antimicrobial [1,2].
  • Phytotoxic [3].
  • Specific acetylcholinesterase (AChE) inhibitor [4].
Product References
  1. Studies in the biochemistry of microorganisms. 93. Cyclopenin, a nitrogen-containing metabolic product of Penicillium cyclopium Westling: A. Bracken, et al.; Biochem. J. 57, 587 (1954)
  2. On the biosynthesis of cyclopenin and cyclopenol, benzodiazepine alkaloids from Penicillium cyclopium Westling: L. Nover & M. Luckner; Eur. J. Biochem. 10, 268 (1969)
  3. The Biological Properties of Cyclopenin and Cyclopenol: H.G. Cutler, et al.; Plant and Cell Physiol. 25, 257 (1984)
  4. Arisugacins A and B, novel and selective acetylcholinesterase inhibitors from Penicillium sp. FO-4259. I. Screening, taxonomy, fermentation, isolation and biological activity: F. Kuno, et al.; J. Antibiot. 49, 742 (1996)
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