AdipoGen Life Sciences

Altersolanol A

CHF 190.00
In stock
AG-CN2-0436-M0011 mgCHF 190.00
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Product Details
Synonyms Stemphylin; NSC 173943
Product Type Chemical
Properties
Formula

C16H16O8

MW 336.3
CAS 22268-16-2
Source/Host Chemicals Isolated from Alternaria sp.
Purity Chemicals ≥97% (HPLC)
Appearance Yellow-orange to brown solid.
Solubility Soluble in DMSO or ethanol.
Identity Determined by 1H-NMR.
InChi Key VSMBLBOUQJNJIL-JJXSEGSLSA-N
Smiles [H][C@@]12C=CC(=O)[C@@]1(C)[C@@H](O)[C@H]1[C@@H](C[C@H]2C)OC(=O)C1=C
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Anticancer compound.
  • Apoptosis inducer.
  • Anti-angiogenic.
  • Anti-inflammatory.
  • Antibacterial.
  • Phytotoxic.
Product References
  1. High-performance liquid chromatographic determination of macrosporin, altersolanol A, alterporriol A, B and C in fermentation of Alternaria porri (Ellis) Ciferri: R. Suemitsu, et al.; J. Chromatogr. 454, 406 (1988)
  2. Mode of phytotoxic action of altersolanols: H. Haraguchi, et al.; Phytochemistry 43, 989 (1996)
  3. Biologically active polyketide metabolites from an undetermined fungicolous hyphomycete resembling Cladosporium: U. Hoeller, et al.; J. Nat. Prod. 54, 876 (2002)
  4. Secondary metabolite profiling of Alternaria dauci, A. porri, A. solani, and A. tomatophila: B. Andersen, et al.; Mycol. Res. 112, 241 (2008)
  5. Anticancer effect of altersolanol A, a metabolite produced by the endophytic fungus Stemphylium globuliferum, mediated by its pro-apoptotic and anti-invasive potential via the inhibition of NF-κB activity: M.H. Teiten, et al.; Bioorg. Med. Chem. 21, 3850 (2013)
  6. Antiangiogenetic effects of anthranoids from Alternaria sp., an endophytic fungus in a Thai medicinal plant Erythrina variegata: P. Pompeng, et al.; Phytomedicine 20, 918 (2013)
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