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AdipoGen Life Sciences
Altersolanol A
190
CHF
CHF 190.00
In stock
AG-CN2-0436-M0011 mgCHF 190.00
| Product Details | |
|---|---|
| Synonyms | Stemphylin; NSC 173943 |
| Product Type | Chemical |
| Properties | |
| Formula |
C16H16O8 |
| MW | 336.3 |
| CAS | 22268-16-2 |
| Source/Host Chemicals | Isolated from Alternaria sp. |
| Purity Chemicals | ≥97% (HPLC) |
| Appearance | Yellow-orange to brown solid. |
| Solubility | Soluble in DMSO or ethanol. |
| Identity | Determined by 1H-NMR. |
| InChi Key | VSMBLBOUQJNJIL-JJXSEGSLSA-N |
| Smiles | [H][C@@]12C=CC(=O)[C@@]1(C)[C@@H](O)[C@H]1[C@@H](C[C@H]2C)OC(=O)C1=C |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Anticancer compound.
- Apoptosis inducer.
- Anti-angiogenic.
- Anti-inflammatory.
- Antibacterial.
- Phytotoxic.
Product References
- High-performance liquid chromatographic determination of macrosporin, altersolanol A, alterporriol A, B and C in fermentation of Alternaria porri (Ellis) Ciferri: R. Suemitsu, et al.; J. Chromatogr. 454, 406 (1988)
- Mode of phytotoxic action of altersolanols: H. Haraguchi, et al.; Phytochemistry 43, 989 (1996)
- Biologically active polyketide metabolites from an undetermined fungicolous hyphomycete resembling Cladosporium: U. Hoeller, et al.; J. Nat. Prod. 54, 876 (2002)
- Secondary metabolite profiling of Alternaria dauci, A. porri, A. solani, and A. tomatophila: B. Andersen, et al.; Mycol. Res. 112, 241 (2008)
- Anticancer effect of altersolanol A, a metabolite produced by the endophytic fungus Stemphylium globuliferum, mediated by its pro-apoptotic and anti-invasive potential via the inhibition of NF-κB activity: M.H. Teiten, et al.; Bioorg. Med. Chem. 21, 3850 (2013)
- Antiangiogenetic effects of anthranoids from Alternaria sp., an endophytic fungus in a Thai medicinal plant Erythrina variegata: P. Pompeng, et al.; Phytomedicine 20, 918 (2013)
- Fungal metabolite altersolanol a exhibits potent cytotoxicity against human placental trophoblasts in vitro via mitochondria‑mediated apoptosis: T. Gu, et al.; Mycotox. Res. 40, 419 (2024)
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