Altersolanol A

More Information
Product Details
Synonyms	Stemphylin; NSC 173943
Product Type	Chemical
Properties
Formula	C₁₆H₁₆O₈
MW	336.3
CAS	22268-16-2
Source/Host Chemicals	Isolated from Alternaria sp.
Purity Chemicals	≥97% (HPLC)
Appearance	Yellow-orange to brown solid.
Solubility	Soluble in DMSO or ethanol.
Identity	Determined by ¹H-NMR.
InChi Key	VSMBLBOUQJNJIL-JJXSEGSLSA-N
Smiles	[H][C@@]12C=CC(=O)[C@@]1(C)[C@@H](O)[C@H]1[C@@H](C[C@H]2C)OC(=O)C1=C
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Description

Product References

High-performance liquid chromatographic determination of macrosporin, altersolanol A, alterporriol A, B and C in fermentation of Alternaria porri (Ellis) Ciferri: R. Suemitsu, et al.; J. Chromatogr. 454, 406 (1988)
Mode of phytotoxic action of altersolanols: H. Haraguchi, et al.; Phytochemistry 43, 989 (1996)
Biologically active polyketide metabolites from an undetermined fungicolous hyphomycete resembling Cladosporium: U. Hoeller, et al.; J. Nat. Prod. 54, 876 (2002)
Secondary metabolite profiling of Alternaria dauci, A. porri, A. solani, and A. tomatophila: B. Andersen, et al.; Mycol. Res. 112, 241 (2008)
Anticancer effect of altersolanol A, a metabolite produced by the endophytic fungus Stemphylium globuliferum, mediated by its pro-apoptotic and anti-invasive potential via the inhibition of NF-κB activity: M.H. Teiten, et al.; Bioorg. Med. Chem. 21, 3850 (2013)
Antiangiogenetic effects of anthranoids from Alternaria sp., an endophytic fungus in a Thai medicinal plant Erythrina variegata: P. Pompeng, et al.; Phytomedicine 20, 918 (2013)
Fungal metabolite altersolanol a exhibits potent cytotoxicity against human placental trophoblasts in vitro via mitochondria‑mediated apoptosis: T. Gu, et al.; Mycotox. Res. 40, 419 (2024)

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