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AdipoGen Life Sciences
Sekikaic acid
230
CHF
CHF 230.00
In stock
AG-CN2-0502-M0011 mgCHF 230.00
| Product Details | |
|---|---|
| Synonyms | 2-Hydroxy-3-(2-hydroxy-4-methoxy-6-propylbenzoyl)oxy-4-methoxy-6-propylbenzoic acid; Sekicic acid |
| Product Type | Chemical |
| Properties | |
| Formula |
C22H26O8 |
| MW | 418.4 |
| CAS | 607-11-4 |
| Source/Host Chemicals | Isolated from Ramalina sp. |
| Purity Chemicals | ≥96% (HPLC) |
| Appearance | Solid. |
| Solubility | Soluble in DMSO, ethanol or methanol. |
| Identity | Determined by 1H-NMR and MS. |
| InChi Key | CPHXGYQLOSNELY-UHFFFAOYSA-N |
| Smiles | OC1=CC(OC)=CC(CCC)=C1C(OC2=C(OC)C=C(CCC)C(C(O)=O)=C2O)=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antioxidant. Reactive oxygen species (ROS) scavenger.
- Specific ligand of the coactivator CBP/p300, binding to the GACKIX domain. Efficiently inhibits binding of activators at two binding sites.
- Antibiotic. Potent antibacterial compound.
- Antifungal on selected fungi species.
- Antiviral agent. Interferes with the viral replication of selected respiratory syncytial virus.
- Competitive α-glucosidase and non-competitive β-glucosidase inhibitor.
- Shows moderate anticancer activity.
Product References
- Phytochemical investigation of the Australian lichens Ramalina glaucescens and Xanthoria parietina: D.A. Dias, et al.; Nat. Prod. Commun. 4, 959 (2009)
- Antioxidant activities of edible lichen Ramalina conduplicans and its free radical-scavenging constituents: H. Luo, et al.; Mycosci. 51, 391 (2010)
- Antioxidant activity of some lichen metabolites: V.M. Thadhani, et al.; Nat. Prod. Res. 25, 1827 (2011)
- Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300: C.Y. Majmudar, et al.; Angew. Chem. Int. Ed. Engl. 51, 11258 (2011)
- Antimicrobial and toxicological activities of some depsides and depsidones: V.M. Thadhani, et al.; J. Natn. Sci. Found. Sri Lanka 40, 43 (2012)
- Glucosidase inhibitory and radical scavenging properties of lichen metabolites Salazinic acid, Sekikaic acid and Usnic acid: L.M. Salazinik, et al.; Hacettepe J. Biol. Chem. 40, 7 (2012)
- Antibacterial and antioxidant activity of lichen species Ramalina roesleri: R. Sisodia, et al.; Nat. Prod. Res. 27, 2235 (2013)
- Phenolic compounds with in vitro activity against respiratory syncytial virus from the Nigerian lichen Ramalina farinacea: D. Lai, et al.; Planta Med. 79, 1440 (2013)
- Chemistry and Biological Activity of Ramalina Lichenized Fungi: A.S. Moreira, et al.; Molecules 20, 8952 (2015) (Review)
- Biopharmaceutical potential of two Ramalina lichens and their metabolites: S. Ristic, et al.; Curr. Pharm. Biotechnol. 17, 651 (2016)