AdipoGen Life Sciences

BQ-788 . sodium salt

CHF 220.00
In stock
AG-CP3-0012-C500500 µgCHF 220.00
AG-CP3-0012-M0011 mgCHF 290.00
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Product Details
Synonyms ETB Receptor Antagonist; N-[(cis-2,6-Dimethyl-1-piperidinyl)carbonyl]-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-D-norleucine
Product Type Chemical
Properties
Formula

C34H50N5O7 . Na

MW 640.8 . 23.0
CAS 156161-89-6
Source/Host Chemicals Synthetic.
Purity Chemicals ≥95% (HPLC)
Appearance White to off-white solid.
Solubility Soluble in DMSO, 0.1M sodium bicarbonate or 100% ethanol. Slightly soluble in methanol. Insoluble in water.
InChi Key QCVIFBRTTLMEOV-FUKQNADPSA-M
Smiles CCCC[C@@H](NC(=O)[C@@H](CC1=CN(C(=O)OC)C2=C1C=CC=C2)NC(=O)[C@H](CC(C)(C)C)NC(=O)N1[C@@H](C)CCC[C@H]1C)C(=O)O[Na]
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Potent and selective endothelin B receptor (ETBR) antagonist.
Product References
  1. Clearance of circulating endothelin-1 by ETB receptors in rats: T. Fukuroda, et al.; BBRC 199, 1461 (1994)
  2. Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788: K. Ishikawa, et al.; PNAS 91, 4892 (1994)
  3. Novel antagonist of endothelin ETB1 and ETB2 receptors, BQ-788: effects on blood vessel and small intestine: H. Karaki, et al.; BBRC 205, 168 (1994)
  4. PD 142893, SB 209670, and BQ 788 selectively antagonize vascular endothelial versus vascular smooth muscle ET(B)-receptor activity in the rat: R.L. Schroeder, et al.; J. Cardiovasc. Pharmacol. 32, 935 (1998)
  5. BQ-788, a selective endothelin ETB receptor antagonist: M. Okada & M. Nishikibe; Cardiovasc. Drug Rev. 20, 53 (2002)
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