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AdipoGen Life Sciences
Bisindolylmaleimide II
70
CHF
CHF 70.00
In stock
AG-CR1-0010-M0011 mgCHF 70.00
AG-CR1-0010-M0055 mgCHF 210.00
| Product Details | |
|---|---|
| Synonyms | BIM II |
| Product Type | Chemical |
| Properties | |
| Formula |
C27H26N4O2 |
| MW | 438.5 |
| CAS | 137592-45-1 |
| Purity Chemicals | ≥97% (mixture of 2 isomers) (NMR) |
| Appearance | Orange solid. |
| Solubility | Soluble in DMSO or 100% ethanol. |
| Identity | Determined by 1H-NMR. |
| InChi Key | LBFDERUQORUFIN-UHFFFAOYSA-N |
| Smiles | CN1CCCC1CCN1C=C(C2=C1C=CC=C2)C1=C(C(=O)NC1=O)C1=CNC2=C1C=CC=C2 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Protein kinase C (PKC) inhibitor [1, 2].
- Binds with reversed orientation to protein kinase A (PKA) [1].
Product References
- The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C: D. Toullec, et al.; J. Biol. Chem. 266, 15771 (1991)
- The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A: M. Gassel, et al.; J. Biol. Chem. 279, 23679 (2004)
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