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AdipoGen Life Sciences
MK-571 . sodium salt
70
CHF
CHF 70.00
In stock
AG-CR1-0021-M0055 mgCHF 70.00
AG-CR1-0021-M02525 mgCHF 280.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula |
C26H26ClN2O3S2 . Na |
| MW | 514.1 . 23.0 |
| CAS | 115103-85-0 | 115104-28-4 (free base) |
| Purity Chemicals | ≥97% (NMR) |
| Appearance | Light yellow solid. |
| Solubility | Soluble in water (20 mg/ml), 100% ethanol (10 mg/ml), DMSO or methanol. |
| Identity | Determined by 1H-NMR. |
| Other Product Data |
Aqueous stock solutions may be stable for more than 24 hours but we recommend making a fresh preparation before use. |
| InChi Key | XNAYQOBPAXEYLI-AAGWESIMSA-M |
| Smiles | [Na+].CN(C)C(=O)CCSC(SCCC([O-])=O)C1=CC(\C=C\C2=CC=C3C=CC(Cl)=CC3=N2)=CC=C1 |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Hygroscopic. Protect from light. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Selective leukotriene LTD4 receptor antagonist [1].
- Potent multidrug resistance-associated protein MRP1 and MRP2 inhibitor [2,4].
- Antinociceptive [3].
Product References
- Pharmacology of L-660,711 (MK-571): a novel potent and selective leukotriene D4 receptor antagonist: T.R. Jones, et al.; Can. J. Physiol. Pharmacol. 67, 17 (1989)
- The leukotriene LTD4 receptor antagonist MK571 specifically modulates MRP associated multidrug resistance: V. Gekeler, et al.; BBRC 208, 345 (1995)
- The antinociceptive effect of leukotriene D(4) receptor antagonist, MK-571, in mice: possible involvement of opioidergic mechanism: Eur. J. Pharmacol. 386, 195 (1999)
- Inhibition of Glucose Transport by Tomatoside A, a Tomato Seed Steroidal Saponin, through the Suppression of GLUT2 Expression in Caco-2 Cells: J. Agric. Food Chem. ahead of print 2018