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AdipoGen Life Sciences
(-)-Indolactam V
220
CHF
CHF 220.00
In stock
AG-CR1-0041-C300300 µgCHF 220.00
Product Details | |
---|---|
Product Type | Chemical |
Properties | |
Formula |
C17H23N3O2 |
MW | 301.4 |
CAS | 90365-57-4 |
RTECS | UY8547000 |
Purity Chemicals | ≥95% |
Appearance | Off-white to light yellow solid. |
Solubility | Soluble in DMSO or 100% ethanol. |
Identity | Determined by 1H-NMR. |
Other Product Data |
May contain traces of (+)-Indolactam V. |
InChi Key | LUZOFMGZMUZSSK-LRDDRELGSA-N |
Smiles | CC(C)[C@@H]1N(C)C2=CC=CC3=C2C(C[C@@H](CO)NC1=O)=CN3 |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Protect from light. |
Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
Description
- Tumor promoter [1].
- Protein kinase C (PKC) inducer [2].
- Mitogenesis activator [3].
- Differentiation inducer [4].
Product References
- Structure-activity studies on synthetic analogues (indolactams) of the tumor promoter teleocidin: H. Fujiki, et al.; Gann 75, 866 (1984)
- (-)-Indolactam V activates protein kinase C and induces changes in muscarinic receptor functions in SH-SY5Y human neuroblastoma cells: J. Heikkilä & K. Akerman; BBRC 162, 1207 (1989)
- (-)-Indolactam V-induced mitogenesis in human fetal/neonatal and adult T cells: lower response of neonatal cells and possible regulatory role of monocytes in protein kinase C-mediated pathways: N. Papadogiannakis; Cell. Immunol. 162, 288 (1995)
- A small molecule that directs differentiation of human ESCs into the pancreatic lineage: S. Chen, et al.; Nat. Chem. Biol. 5, 258 (2009)
- Angiopoietins stimulate pancreatic islet development from stem cells: S.S. Karanth, et al.; Nature Sci. Rep. 11, 13558 (2021)