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AdipoGen Life Sciences
Bisindolylmaleimide IV
80
CHF
CHF 80.00
In stock
AG-CR1-0152-M0011 mgCHF 80.00
AG-CR1-0152-M0055 mgCHF 240.00
| Product Details | |
|---|---|
| Synonyms | Ro 31-6233; Arcyriarubin A; BIM IV; 2,3-bis(1H-Indol-3-yl)maleimide |
| Product Type | Chemical |
| Properties | |
| Formula |
C20H13N3O2 |
| MW | 327.3 |
| CAS | 119139-23-0 |
| Purity Chemicals | ≥98% (NMR) |
| Appearance | Red to orange solid. |
| Solubility | Soluble in DMSO, ethanol, methanol or dimethylformamide. |
| Identity | Determined by 1H-NMR. |
| InChi Key | DQYBRTASHMYDJG-UHFFFAOYSA-N |
| Smiles | O=C1NC(=O)C(C2=CNC3=C2C=CC=C3)=C1C1=CNC2=C1C=CC=C2 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability |
Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Cell permeable protein kinase C (PKC) inhibitor [1-3].
- Inhibits also protein kinase A (PKA) [1,2].
Product References
- The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C: D. Toullec, et al.; J. Biol. Chem. 266, 15771 (1991)
- Inhibitors of protein kinase C. 1. 2,3-Bisarylmaleimides: P.D. Davis, et al.; J. Med. Chem. 35, 177 (1992)
- Muscarinic interactions of bisindolylmaleimide analogues: S. Lazareno, et al.; Eur. J. Pharmacol. 360, 281 (1998)
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