BMS-3

CHF 95.00
In stock
AG-CR1-2901-M0055 mgCHF 95.00
AG-CR1-2901-M02525 mgCHF 380.00
 
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Product Details
Synonyms N-(5-(1-(2,6-Dichlorophenyl)-3-(difluoromethyl)-1H-pyrazol-5-yl)thiazol-2- yl)cyclopropanecarboxamide
Product Type Chemical
Properties
Formula C17H12Cl2F2N4OS
MW 429.3
CAS 1338247-30-5
Purity Chemicals ≥98% (HPLC)
Appearance Off-white solid.
Solubility Soluble in DMSO (5mg/ml).
InChi Key YBGGBHCJSAEIAS-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Potent LIMK (Lim kinase) inhibitor. Has IC50 values of 5nM and 6nM for LIMK1 and LIMK2, respectively.
Product References
  1. Phenyl-substituted pyrimidine compounds useful as kinase inhibitors: S.T. Wrobelski, et al.; WO2006084017 (2006)
  2. Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors: P. Ross-Macdonald, et al.; Mol. Cancer Ther. 7, 3490 (2008)
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