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AdipoGen Life Sciences
Shz-1
40
CHF
CHF 40.00
In stock
AG-CR1-3502-M0011 mgCHF 40.00
AG-CR1-3502-M0055 mgCHF 120.00
| Product Details | |
|---|---|
| Synonyms | Sulfonylhydrazone-1; 2-[(5-Bromo-2-hydroxyphenyl)methylene]hydrazide benzenesulfonic acid |
| Product Type | Chemical |
| Properties | |
| Formula |
C13H11BrN2O3S |
| MW | 355.2 |
| CAS | 326886-05-9 |
| Purity Chemicals | ≥95% (NMR) |
| Appearance | White to yellow solid. |
| Solubility | Soluble in DMSO (at least 5 mg/ml). |
| InChi Key | OEMCLQLAWYKPRK-OQLLNIDSSA-N |
| Smiles | OC1=C(\C=N\NS(=O)(=O)C2=CC=CC=C2)C=C(Br)C=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Enhancer of myocardial regenerative repair by stem cells [1].
- Potent inducer of Homeobox protein Nkx2.5 and a subset of other cardiac markers, including myocardin, and sarcomeric-tropomyosin (SαTM) in a variety of different stem/progenitor cells [1].
Product References
- Cardiogenic small molecules that enhance myocardial repair by stem cell: H. Sadek, et al.; PNAS 105, 6063 (2008)
- Synthetic sulfonyl-hydrazone-1 positively regulates cardiomyogenic microRNA expression and cardiomyocyte differentiation of induced pluripotent stem cells: M. Quattrocelli, et al.; J. Cell Biochem. 112, 2006 (2011)
- Expression of sarcomeric tropomyosin in striated muscles in axolotl treated with shz-1, a small cardiogenic molecule: Ch. Nan, et al.; Cardiovasc. Toxicol. 15, 29 (2015)