AdipoGen Life Sciences

α-Galactosylceramide Analog 8

CHF 290.00

In stock

AG-CR1-3622-C500500 µgCHF 290.00

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Product Details
Synonyms	α-Gal-Cer Analog 8; α-Galactosylceramide Analog 5; α-Gal-Cer Analog 5
Product Type	Chemical
Properties
Formula	C₅₀H₉₇N₃O₈
MW	868.3
CAS	922727-14-8
Source/Host Chemicals	Synthetic.
Purity Chemicals	≥96% (NMR)
Appearance	White solid.
Solubility	Soluble in pyridine, methanol, 100% ethanol, DMSO or dimethylformamide.
Identity	Identity determined by ¹H-NMR.
InChi Key	YLAIBGQPPXWHSD-MKADWPIHSA-N
Smiles	CCCCCCCCCCCCCCCCCCCCCCCCC1=CN(N=N1)[C@@H](COC1OC(CO)C(O)C(O)C1O)[C@H](O)[C@H](O)CCCCCCCCCCCCCC
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Aliquot into glass vials.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Description

Immunostimulant.
Potent stimulator of natural killer T (NKT) cells.
Specific ligand of the lipid-binding MHC class I-like protein CD1d in human and mouse NKT cells.
Potent antitumor compound.
Stimulates the production of smaller amounts of IFN-γ than α-GalCer, but induces equal or greater IL-4 secretion in mouse models.

Product References

Synthesis and evaluation of 1,2,3-triazole containing analogues of the immunostimulant alpha-GalCer: T. Lee, et al.; J. Med. Chem. 50, 585 (2007)
Phase transfer agent assisted biphasic CuAAC reaction: J.H. Kim & S. Kim; RSC Adv. 4, 26516 (2014)

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