α-Galactosylceramide Analog 8

CHF 280.00
In stock
AG-CR1-3622-C500500 µgCHF 280.00
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Product Details
Synonyms α-Gal-Cer Analog 8; α-Galactosylceramide Analog 5; α-Gal-Cer Analog 5
Product Type Chemical
Properties
Formula C50H97N3O8
MW 868.3
CAS 922727-14-8
Source/Host Chemicals Synthetic.
Purity Chemicals ≥96% (NMR)
Appearance White solid.
Solubility Soluble in pyridine, methanol, 100% ethanol, DMSO or dimethylformamide.
Identity Identity determined by 1H-NMR.
InChi Key YLAIBGQPPXWHSD-MKADWPIHSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Aliquot into glass vials.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Immunostimulant.
  • Potent stimulator of natural killer T (NKT) cells.
  • Specific ligand of the lipid-binding MHC class I-like protein CD1d in human and mouse NKT cells.
  • Potent antitumor compound.
  • Stimulates the production of smaller amounts of IFN-γ than α-GalCer, but induces equal or greater IL-4 secretion in mouse models.
Product References
  1. Synthesis and evaluation of 1,2,3-triazole containing analogues of the immunostimulant alpha-GalCer: T. Lee, et al.; J. Med. Chem. 50, 585 (2007)
  2. Phase transfer agent assisted biphasic CuAAC reaction: J.H. Kim & S. Kim; RSC Adv. 4, 26516 (2014)
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