DYRK1 Inhibitor Negative Control AnnH79
|Purity Chemicals||≥98% (HPLC, NMR)|
|Appearance||Off-white to pale yellow solid.|
|Solubility||Soluble in DMSO.|
|Identity||Determined by 1H-NMR.|
|Other Product Data||
DMSO Stock Solution: Prior to performing biological experiments the DMSO stock solution should be further diluted into water or other aqueous buffers to ensure that the residual amount of DMSO is insignificant, since DMSO may have physiological effects at high concentrations.
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
Keep cool and dry.
Protect from light and moisture.
|Use/Stability||Stable for at least 2 years after receipt when stored at -20°C.|
|Product Specification Sheet|
- Inactive harmine analog that does not inhibit DYRK1A/DYRK1B.
- Useful as negative control for β-carboline analog DYRK1A/B inhibitors.
- Selectivity profiling and biological activity of novel β-carbolines as potent and selective DYRK1 kinase inhibitors: K. Rüben, et al.; PLos One 10, e0132453 (2015)