DYRK1 Inhibitor Negative Control AnnH79

CHF 180.00
In stock
AG-CR1-3652-C500500 µgCHF 180.00
More Information
Product Details
Synonyms 2-(1-Bromo-7,8-dichloro-9H-pyrido[3,4-b]indol-9-yl)acetonitrile; AnnH79
Product Type Chemical
Properties
Formula

C13H6BrCl2N3

MW 355.0
Purity Chemicals ≥98% (HPLC, NMR)
Appearance Off-white to pale yellow solid.
Solubility Soluble in DMSO.
Identity Determined by 1H-NMR.
Other Product Data

DMSO Stock Solution: Prior to performing biological experiments the DMSO stock solution should be further diluted into water or other aqueous buffers to ensure that the residual amount of DMSO is insignificant, since DMSO may have physiological effects at high concentrations.

InChi Key VJUNHKYSEMGQTK-UHFFFAOYSA-N
Smiles ClC1=CC=C2C(N(CC#N)C3=C2C=CN=C3Br)=C1Cl
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Inactive harmine analog that does not inhibit DYRK1A/DYRK1B.
  • Useful as negative control for β-carboline analog DYRK1A/B inhibitors.
Product References
  1. Selectivity profiling and biological activity of novel β-carbolines as potent and selective DYRK1 kinase inhibitors: K. Rüben, et al.; PLos One 10, e0132453 (2015)
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