anti-CD3 (human), mAb (UCHT1) (Fab)
|Product Type||Monoclonal Antibody|
|Immunogen/Antigen||Human thymocytes/Sezary T cells.|
Clone UCHT1 recognizes the 20kDa epsilon chain of the CD3 molecule complex.
|Formulation||50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl|
|Isotype Negative Control|
|Other Product Data||
Click here for Original Manufacturer Product Datasheet
|Declaration||Manufactured by Ancell Corporation.|
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||+4°C|
|Handling Advice||Avoid freeze/thaw cycles.|
|Use/Stability||Stable for at least 1 year after receipt when stored at +4°C.|
|Product Specification Sheet|
The human CD3/T cell receptor (TcR) complex is made up of the CD3 proteins (γ, δ, 2 ε) and teh ζ-chain in association with either α/β or γ/δ proteins of the TcR. The TcR recognizes antigens in association with MHC molecules after which protein chains of the CD3 complex mediate activation signals triggered by TcR antigen binding. CD3 is expressed on greater than 95% of circulating human peripheral T cells.