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Ancell
anti-CD3 (human), mAb (UCHT1) (Biotin)
306
CHF
CHF 306.00
In stock
ANC-144-030100 µgCHF 306.00
| Product Details | |
|---|---|
| Synonyms | CD3ε; CD3e |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | UCHT1 |
| Isotype | Mouse IgG1 |
| Immunogen/Antigen | Human thymocytes/Sezary T cells. |
| Label/Conjugates | Biotin |
| Application |
Flow Cytometry |
| Crossreactivity | Human |
| Specificity |
Clone UCHT1 recognizes the 20kDa epsilon chain of the CD3 molecule complex. |
| Formulation | 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). |
| Isotype Negative Control | |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Ancell Corporation. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
The human CD3/T cell receptor (TcR) complex is made up of the CD3 proteins (γ, δ, 2 ε) and teh ζ-chain in association with either α/β or γ/δ proteins of the TcR. The TcR recognizes antigens in association with MHC molecules after which protein chains of the CD3 complex mediate activation signals triggered by TcR antigen binding. CD3 is expressed on greater than 95% of circulating human peripheral T cells.
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