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Ancell
anti-CD18 (human), mAb (IB4) (Fab)
1416
CHF
CHF 1'416.00
In stock
ANC-167-580100 µgCHF 1'416.00
| Product Details | |
|---|---|
| Synonyms | Integrin β-2 |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | IB4 |
| Isotype | Mouse IgG2a |
| Immunogen/Antigen | Human peripheral blood monocytes. |
| Label/Conjugates | Preservative Free |
| Application |
Flow Cytometry |
| Crossreactivity |
Human Primate Rabbit |
| Purity | Protein A purified. |
| Purity Detail | Antibody was Protein A purified from (low FBS containing) tissue culture supernatant. Immunoglobulin was enzymaticly cleaved using Pepsin. Fab was separated from F(ab’)2 and intact antibody and Fc fragments by Protein A and Size exclusion chromatography. |
| Concentration | 1mg/ml |
| Formulation | 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl. Preservative free. |
| Isotype Negative Control | |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Ancell Corporation. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice |
Avoid freeze/thaw cycles. Keep sterile. |
| Use/Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Human CD18 (β2 integrin) forms a heterodimer with either αL, αM, or αX integrins (CD11a, b or c). CD11/CD18 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. Antibody IB4 recognizes the beta 2 integrin subunit (CD18) adhesion molecule of about 95 kd. Antibody IB4 blocks binding of ICAM-1 and ICAM-3 to LFA-1.
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