anti-CD155 [PVR] (human), mAb (ANC2B2) (R-PE)

CHF 448.00
In stock
ANC-255-050120 testsCHF 448.00
More Information
Product Details
Synonyms PVR; Polio Virus Receptor; Necl-5
Product Type Monoclonal Antibody
Properties
Clone ANC2B2
Isotype Mouse IgG1κ
Source/Host Purified from concentrated hybridoma tissue culture supernatant.
Immunogen/Antigen Recombinant human CD155.
Label/Conjugates R-PE
Application

ELISA
Flow Cytometry

Crossreactivity Human
Specificity

Binds to human cell surface CD155 on U-937 cells, and binds to recombinant human CD155 in EIA.

Purity ≥95% (SDS-PAGE)
Purity Detail Protein A purified.
Concentration 1mg/ml
Formulation 50mM Sodium Phosphate pH 7.5, 500mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Isotype Negative Control

Mouse IgG1 Isotype Control (R-PE)

Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Accession Number P15151
Declaration Manufactured by Ancell Corporation.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Do not freeze.
Protect from light.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Human CD155 (Polio Virus Receptor, PVR, Necl-5) is a 70kd type I Ig superfamily molecule. It is involved in formation of intracellular junctions between epithelial cells. Its ligands include CD226 (DNAM-1), and CD96 (TACTILE). CD155 expression by tumor has been shown to be upregulated by nitric oxide. A soluble version of CD155 has been shown to exist. High CD155 expression has recently been exploited to use engineered poliovirus to treat glioblastoma.

© 2017 Adipogen Life Sciences. Pictures: © 2012 Martin Oeggerli. All Rights Reserved.