Ancell

anti-CD155 [PVR] (human), mAb (ANC2B2) (preservative-free)

CHF 306.00

In stock

ANC-255-820100 µgCHF 306.00

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Product Details
Synonyms	PVR; Polio Virus Receptor; Necl-5
Product Type	Monoclonal Antibody
Properties
Clone	ANC2B2
Isotype	Mouse IgG1κ
Source/Host	Purified from concentrated hybridoma tissue culture supernatant.
Immunogen/Antigen	Recombinant human CD155.
Label/Conjugates	Preservative Free
Application	ELISA Flow Cytometry
Crossreactivity	Human
Specificity	Binds to human cell surface CD155 on U-937 cells, and binds to recombinant human CD155 in EIA.
Purity	≥95% (SDS-PAGE)
Purity Detail	Protein A purified.
Concentration	1mg/ml
Formulation	50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl.
Isotype Negative Control	Mouse IgG1 Isotype Control (preservative free)
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
Accession Number	P15151
Declaration	Manufactured by Ancell Corporation.
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Avoid freeze/thaw cycles. Keep sterile.
Use/Stability	Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

Human CD155 (Polio Virus Receptor, PVR, Necl-5) is a 70kd type I Ig superfamily molecule. It is involved in formation of intracellular junctions between epithelial cells. Its ligands include CD226 (DNAM-1), and CD96 (TACTILE). CD155 expression by tumor has been shown to be upregulated by nitric oxide. A soluble version of CD155 has been shown to exist. High CD155 expression has recently been exploited to use engineered poliovirus to treat glioblastoma.

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