Ancell

anti-CD105 (human), mAb (SN6) (APC)

CHF 551.00
In stock
ANC-326-060120 testsCHF 551.00
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Product Details
Synonyms Endoglin
Product Type Monoclonal Antibody
Properties
Clone SN6 / N1-3A1
Isotype Mouse IgG1κ
Source/Host Purified from concentrated hybridoma tissue culture supernatant.
Immunogen/Antigen Membrane preparation of human B-lineage leukemia cells.
Label/Conjugates APC
Application

Flow Cytometry
Functional Application: Augments binding of TGF-ß1 to CD105 expressing leukemia cells.
Immunohistochemistry

Crossreactivity Horse
Human
Pig
Primate
Specificity

Recognizes an extracellular epitope of the human CD105 homodimer.

Purity Protein A purified.
Formulation 50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Isotype Negative Control

Mouse IgG1 Isotype Control (APC)

Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by Ancell Corporation.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Do not freeze.
Protect from light.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF
Description

Human CD105 (endoglin) is a homodimeric membrane glycoprotein virtually restricted to endothelial cells and present on some leukemia cells and minor subsets of bone marrow cells. CD105 binds to TGF-β1 and β3 with high affinity.

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