Ancell

anti-CD152 (human), mAb (ANC152.2/8H5) (Biotin)

CHF 423.00

In stock

ANC-359-030100 µgCHF 423.00

More Information
Product Details
Synonyms	CTLA-4
Product Type	Monoclonal Antibody
Properties
Clone	ANC152.2/8H5
Isotype	Mouse IgG1κ
Immunogen/Antigen	Stimulated human PBL’s and human CD152 Ig fusion protein.
Label/Conjugates	Biotin
Application	Flow Cytometry ELISA Functional: Blocks the binding of recombinant CD152-mulg fusion protein/R-PE conjugate (Catalog # ANC-501-050) to CD80 and CD86 expressed on human Raji cells.
Crossreactivity	Cat Cow Dog Human Pig
Formulation	50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Isotype Negative Control	Mouse IgG1 Isotype Control (Biotin)
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
Declaration	Manufactured by Ancell Corporation.
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Avoid freeze/thaw cycles.
Use/Stability	Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

Human CD152 (CTLA-4) is a cell surface glycoprotein expressed at low levels on activated T cells. CD152 is a high affinity receptor for the costimulatory molecules CD80 (B7-1) and CD86 (B7-2) and appears to function as a negative regulator of T cell activation.

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