CD273 [B7-DC] (human)-muIg Fusion Protein

Specifications / Handling

More Information
Product Details
Synonyms	B7-DC; Programmed Cell Death 1 Ligand 2; PD-L2; PDCD1 Ligand 2
Product Type	Protein
Properties
Source/Host	CHO cells
Crossreactivity	Human
Formulation	50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5 mg/ml Gentamicin Sulfate.
Protein Negative Control	MuIg Control Protein
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
Declaration	Manufactured by Ancell Corporation.
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Avoid freeze/thaw cycles.
Use/Stability	Stable for at least 6 months after receipt when stored at +4°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

CD273 (B7-DC; PD-L2) is a type I surface molecule with homology to CD80, CD86, CD274. It is expressed primarily by dendritic cells and provides a stimulatory signal to CD279 (PD-1; programmed death molecule) which has an important immunoregulatory role by downregulating the T cell response. CD273 binds to CD279 (PD-1) with a 2-6 fold higher affinity than CD274.

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CD273 [B7-DC/PD-L2] (human)-muIg Fusion Protein