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Ancell
anti-CD4 (mouse), mAb (GK1.5) (preservative free)
260
CHF
CHF 260.00
In stock
ANC-704-820100 µgCHF 260.00
| Product Details | |
|---|---|
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | GK1.5 |
| Isotype | Rat IgG2bκ |
| Immunogen/Antigen | Mouse CTL-V4 membrane prep. |
| Label/Conjugates | Preservative Free |
| Application |
Flow Cytometry |
| Crossreactivity | Mouse |
| Specificity |
Binds to an extracellular epitope of the 55kd CD4 molecule present on a murine T cell subset. |
| Purity | ≥95% (SDS-PAGE) |
| Formulation | 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Ancell Corporation. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
CD4 binds to MHC Class II expressed by antigen presenting cells, facilitating T cell receptor signaling.
Product References
- Evidence implicating L3T4 in class II MHC antigen reactivity; monoclonal antibody GK1.5 (anti-L3T4a) blocks class II MHC antigen-specific proliferation, release of lymphokines, and binding by cloned murine helper T lymphocyte lines: D.B. wilde, et al.; J. Immunol. 131, 2178 (1983)
- Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule: D.P. Dialynas, et al.; J. Immunol. 131, 2445 (1983)
- Long-term intratracheal lipopolysaccharide exposure in mice results in chronic lung inflammation and persistent pathology: J.H. Vernooy, et al.; Am. J. Respir. Cell Mol. Biol. 26, 152 (2002)
- Suppression of Alkali Burn-Induced Corneal Neovascularization by Dendritic Cell Vaccination Targeting VEGF Receptor 2: H. Mochimaru, et al.; IOVS 49, 2172 (2008)
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