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BellBrook
PLK1 (human) (rec.) (His) (active) (50µg)
As low as
1125
CHF
CHF 1’125.00
In stock
Only %1 left
BBL-2366-C05050 µgCHF 1’125.00
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| Product Details | |
|---|---|
| Synonyms | Polo-like Kinase 1; PLK-1; Serine/threonine-protein Kinase 13; STPK13 |
| Product Type | Protein |
| Properties | |
| Source/Host | Insect cells |
| Sequence |
Recombinant human PLK1 (aa 1-603) fused to a N-terminal His tag. |
| Crossreactivity | Human |
| Application |
Drug Discovery |
| Biological Activity |
The enzyme has been thoroughly validated with the Transcreener ADP2 Assay Kit. |
| MW | 69.1 kDa |
| Purity | ≥85% (SDS-PAGE) |
| Accession Number | P53350 |
| Formulation | Liquid. In 50mM Tris-HCl pH 8.0, 500mM NaCl, 20% glycerol. |
| Other Product Data |
Click here for Complete Information from the Original Manufacturer Uniprot P53350: PLK1 HUMAN |
| Shipping and Handling | |
| Shipping | DRY ICE |
| Short Term Storage | -20°C |
| Long Term Storage | -80°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 6 months after receipt when stored at -80°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Polo-like kinase 1 (PLK1) is a key serine/threonine kinase that regulates cell cycle progression, ensuring proper mitotic entry, chromosome segregation, and cytokinesis. Overexpression of PLK1 is frequently linked to cancer, making it both a critical regulator of genomic stability and a promising therapeutic target.
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