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BellBrook
Enzolution™ DDX1 ATPase TR-FRET Assay System
CHF 0.00
In stock
BBL-3037-TR-1K1000 assaysCHF 1'252.00
BBL-3037-TR-10K10000 assaysCHF 7'978.00
BBL-3037-TR-100K10 x 10000 assaysINQ
Figure 1: Schematic Overview of the DDX1 ATPase Assay System with the Transcreener® ADP2 Assays.
| Product Details | |
|---|---|
| Synonyms | ATP-dependent RNA Helicase DDX1; DEAD Box Protein 1 |
| Product Type | Kit |
| Properties | |
| Application Set | Compound Screening |
| Crossreactivity | Human |
| Quantity |
1000 assays/384wells (BBL-3037-TR-1K) 10000 assays/384wells (BBL-3037-TR-10K) 100000 assays/384wells (BBL-3037-TR-100K) Note: The exact number of assays depends on enzyme reaction conditions. |
| Detection Type | TR-FRET |
| Kit Contains |
- DDX1 enzyme (human) (rec.) |
| Other Product Data |
Click here for Complete Information from the Original Manufacturer |
| Declaration | Manufactured by BellBrook Labs. |
| Accession Number | Q92499 |
| Shipping and Handling | |
| Shipping | DRY ICE |
| Short Term Storage | -20°C |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Documents | |
| Manual |
 Download PDF |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
The Enzolution DDX1 Assay System provides researchers with an assay tool that will simplify and advance their exploration of novel DDX1/innate immunity modulators. DDX1, a DEAD Box helicase protein characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), is an ATP-dependent RNA helicase that unwinds RNA-RNA and RNA-DNA duplexes. The assay system includes DDX1 enzyme, RNA substrate, assay plates, and buffers to generate a DDX1 enzymatic reaction to produce ADP. The Transcreener ADP TR-FRET Assay (sold separately) is a far-red, competitive assay that directly measures ADP production to determine enzymatic activity with a TR-FRET readout. The Transcreener ADP TR-FRET Assay is not included in the Enzolution Assay System but is available for separate purchases. The Transcreener ADP assay is designed for HTS, Hit-to-Lead, SAR, and general discovery.
When purchasing the DDX1 Assay System, it is important to choose the assay system readout corresponding to the TR-FRET configuration of your Transcreener ADP2 Assay Kit!
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