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BellBrook
Enzolution™ DDX17 ATPase FI Assay System
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Product Details | |
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Synonyms | ATP-dependent RNA Helicase DDX17; DEAD Box Protein 17 |
Product Type | Kit |
Properties | |
Application Set | Compound Screening |
Crossreactivity | Human |
Quantity |
1000 assays/384wells (BBL-3040-FI-1K) 10000 assays/384wells (BBL-3040-FI-10K) 100000 assays/384wells (BBL-3040-FI-100K) Note: The exact number of assays depends on enzyme reaction conditions. |
Detection Type | Fluorescence intensity |
Kit Contains |
- DDX17 (human) (rec.) Enzyme |
Other Product Data |
Click here for Complete Information from the Original Manufacturer |
Declaration | Manufactured by BellBrook Labs. |
Accession Number | Q92841 |
Shipping and Handling | |
Shipping | DRY ICE |
Short Term Storage | -20°C |
Long Term Storage | -20°C |
Handling Advice | Avoid freeze/thaw cycles. |
Documents | |
Manual |
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MSDS | Inquire |
Product Specification Sheet | |
Datasheet |
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The Enzolution DDX17 ATPase Assay System provides researchers with an assay tool that will simplify and advance their exploration of novel DDX17/innate immunity modulators. DDX17, a DEAD Box helicase protein characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), is an ATP-dependent RNA helicase that unwinds RNA and alters RNA structures through ATP binding and hydrolysis. The assay system includes DDX17 enzyme, RNA substrate, assay plates, and buffers to generate a DDX17 enzymatic reaction to produce ADP. The Transcreener ADP FI Assay (sold separately) is a far-red, competitive assay that directly measures ADP production to determine enzymatic activity with a fluorescence intensity (FI) readout. The Transcreener ADP FI Assay is not included in the Enzolution Assay System but is available for separate purchases. The Transcreener ADP assay is designed for HTS, Hit-to-Lead, SAR, and general discovery.
When purchasing the DDX17 ATPase Assay System, it is important to choose the assay system readout corresponding to the FI configuration of your Transcreener ADP2 Assay Kit!