Bertin Bioreagent

anti-Prion Protein, mAb (Sha31)

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BRT-A03213-C200200 µgCHF 609.00
 

Specifications / Handling

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Product Details
Synonyms PrP
Product Type Monoclonal Antibody
Properties
Clone Sha 31
Isotype Mouse IgG1κ
Source/Host Mouse
Immunogen/Antigen This anti-prion protein (PrP) monoclonal antibody was raised against proteinase K treated and non-denatured scrapie-associated fibrils from Syrian hamster infected brain (263K).
Application EIA, Western Blot. For EIA, the optimal working dilution must be determined empirically (currently be-tween 0.1 and 1 µg/mL). For western blot analysis of PrPc, dilute the antibody to a final concentration of 1 µg/mL.
Specificity PrPc (+), PrPsc, (nda) Hamster, (+) Mouse, (nda) Bovine, (+) Ovine, (+) Human.
Formulation Lyophilized. With BSA.
Reconstitution Reconstitute the content of the vial in 1 mL of water.
Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by Bertin Bioreagent
Shipping and Handling
Shipping BLUE ICE
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
Product Specification Sheet
Datasheet Download PDF Download PDF

Scientific Background Information

Product Description
Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its human form, the New Variant of Creutzfeld-Jakob disease. This antibody recognises the human protein sequence within amino acids 145-152 (human numbering).
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