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Bertin Bioreagent
anti-Prion Protein, mAb (BAR 236)
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CHF 579.00
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BRT-A03224-C200200 µgCHF 579.00
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| Product Details | |
|---|---|
| Synonyms | PrP |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | BAR236 |
| Isotype | Mouse IgG2a |
| Source/Host | Mouse |
| Immunogen/Antigen | This anti-Prion Protein Monoclonal Antibody was raised against an ovine recombinant protein. |
| Application | EIA, Flow Cytometry, Western Blot. For western blot analysis of PrPc, dilute to a final concentration of 1 µg/mL and use BSA as blocking reagent. For EIA and flow cytometry, the optimal working must be determined empirically (currently between 0.1 and 1 µg/mL). |
| Specificity | PrPc, (NA*) Hamster, (+) Mouse, (NA*) Bovine, (+) Ovine, (+) Human. |
| Formulation | Lyophilized. With BSA. |
| Reconstitution | Reconstitute the content of the vial in 1 mL of water. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Bertin Bioreagent |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Prion Protein (PrP) and namely its abnormal isoform, partially resistant to proteinase K (PrPres), is the only specific molecular marker of the Transmissible Spongiform Encephalopathies (TSEs) such as Bovine Spongiform Encephalopathie (BSE) or its human form, the New Variant of Creutzfeld-Jakob disease. This antibody recognises the C-terminal part of the protein but it was not possible to identify a continuous epitope for this antibody.