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Bertin Bioreagent
anti-COX2, mAb
As low as
715
CHF
CHF 715.00
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BRT-A03582-C200200 µgCHF 715.00
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| Product Details | |
|---|---|
| Synonyms | Cyclooxygenase-2; PGHS-2; Prostaglandin H Synthase 2 |
| Product Type | Monoclonal Antibody |
| Properties | |
| Source/Host | Mouse |
| Immunogen/Antigen | Human COX-2 amino acid 580-599. |
| Application | EIA |
| Formulation | Liquid. In Phosphate Buffer. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Bertin Bioreagent |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins. The COX component converts arachidonic acid to the hydroperoxy endoperoxide prostaglandin G2 (PGG2), and the peroxidase component reduces the endoperoxide to the corresponding alcohol PGH2. COX2 expression is induced by a variety of stimuli, including phorbol esters, LPS, and cytokines and is responsible for the biosynthesis of PGs under acute inflammatory conditions.