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Bertin Bioreagent
anti-Dihydroergotamine and its main metabolites, pAb
As low as
579
CHF
CHF 579.00
In stock
Only %1 left
BRT-A03610-T500500 dtnCHF 579.00
| Product Details | |
|---|---|
| Synonyms | DHE |
| Product Type | Polyclonal Antibody |
| Properties | |
| Source/Host | Rabbit |
| Immunogen/Antigen | Dihydrolysergic acid-BSA. |
| Application | EIA |
| Formulation | Liquid. In Phosphate Buffer. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Bertin Bioreagent |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | +4°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Dihydroergotamine (DHE) acts on serotonin receptors (particularly 5-HT1 receptors) and alpha-adrenergic receptors in the brain. By stimulating these receptors, DHE causes vasoconstriction (narrowing of blood vessels), which can reduce the blood flow that might be responsible for migraine symptoms. It also has some effects on dopamine receptors. The main metabolites include Dihydroergotamine-N-oxide, 14-hydroxy-dihydroergotamine and Dihydroergocryptine. These metabolites are excreted mainly in the urine.